SURGICAL SITE INFECTION
Clinical trials for SURGICAL SITE INFECTION explained in plain language.
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New wound therapy may lower infection risk after stoma reversal
Disease control CompletedThis study tested whether a special vacuum dressing (negative pressure wound therapy) works better than letting the wound heal naturally after stoma reversal surgery. 72 adults took part, and researchers checked for infection and scar quality. The goal was to find a way to reduce…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: Sindh Institute of Urology and Transplantation • Aim: Disease control
Last updated May 26, 2026 09:02 UTC
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New biologic mesh shows promise for High-Risk hernia patients
Disease control CompletedThis study tested a special collagen mesh (Surgicoll-Mesh®) for hernia repair in 30 patients who were at high risk for infection or had contaminated surgical fields. The goal was to see if this biologic material is safe and works well when synthetic mesh is not a good option. Res…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: Adichunchanagiri Institute of Medical Sciences, B G Nagara • Aim: Disease control
Last updated May 26, 2026 09:00 UTC
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Silver-Lined bone plates aim to stop infections after ankle breaks
Disease control CompletedThis study tested a special silver-coated metal plate (LOQTEQ) for fixing broken ankle bones. The goal was to see if it is safe and works as well as the standard uncoated plate, while possibly reducing infections. About 200 adults with certain ankle fractures took part, and resea…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: aap Implantate AG • Aim: Disease control
Last updated May 26, 2026 08:59 UTC
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Mesh may slash hernia risk after stoma reversal surgery
Disease control CompletedThis study tested whether using a mesh patch to reinforce the surgical site during stoma reversal reduces the chance of developing a hernia, infection, or pain compared to standard closure. 62 adults with temporary stomas took part. The goal is to find a better way to close the s…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 26, 2026 08:35 UTC
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New wound therapy may cut infections after emergency belly surgery
Disease control CompletedThis study tested whether a special wound vacuum (negative pressure therapy) works better than standard stitches to prevent surgical site infections in 50 patients who had emergency abdominal surgery for peritonitis (a serious belly infection). The main goal was to see which meth…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: Medical University of Gdansk • Aim: Disease control
Last updated May 18, 2026 12:12 UTC
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AI text messages slash C-Section infection risk in new study
Prevention CompletedThis study tested whether an artificial intelligence (AI) guide could help prevent surgical site infections in women who had a cesarean section (C-section). 300 women were split into two groups: one received standard care, and the other also got an AI-powered educational guide wi…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: Mansoura University • Aim: Prevention
Last updated May 26, 2026 09:00 UTC
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Simple wash before stitches may slash surgery infections
Prevention CompletedThis study tested whether washing a surgical incision with an antiseptic or salt water solution before closing it can reduce the chance of infection after surgery. Over 2,700 adults having abdominal or groin surgery were randomly assigned to receive one of two types of wound wash…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Prevention
Last updated May 26, 2026 08:54 UTC
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Wisdom tooth antibiotic timing studied to cut infection risk
Prevention CompletedThis study looked at whether giving antibiotics for a shorter time before wisdom tooth removal can still prevent infections. 70 healthy adults having both lower wisdom teeth taken out received either a single dose or multiple doses of IV ampicillin. The main goal was to see how m…
Matched conditions: SURGICAL SITE INFECTION
Phase: PHASE4 • Sponsor: Uji Takeda Hospital • Aim: Prevention
Last updated May 26, 2026 08:32 UTC
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New gel may stop wound infections after belly surgery
Prevention CompletedThis study tested a new treatment called D-PLEX to prevent infections in surgical cuts after abdominal surgery. About 977 adults having colon surgery took part. D-PLEX was given along with standard care, and the team checked for infections over 30 days.
Matched conditions: SURGICAL SITE INFECTION
Phase: PHASE3 • Sponsor: PolyPid Ltd. • Aim: Prevention
Last updated May 26, 2026 08:19 UTC
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New triple wash slashes shoulder surgery infection risk?
Prevention CompletedThis study tested whether adding a benzoyl peroxide gel to standard iodine cleaning could lower the risk of infection from Cutibacterium acnes bacteria during shoulder surgery. 156 patients were split into three groups: iodine only, iodine on skin and deeper layers, or iodine plu…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: Clinique Générale dAnnecy • Aim: Prevention
Last updated May 22, 2026 13:54 UTC
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Simple checklist slashes surgical infection risk in veterans
Prevention CompletedThis study tested whether a simple checklist could reduce dangerous MRSA infections after joint replacement or heart surgery. Over 23,000 veterans took part across 10 VA hospitals. The checklist included steps like testing for MRSA before surgery and using special cleaning method…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Prevention
Last updated May 20, 2026 11:57 UTC
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Which cleanser best prevents c-section infections? large trial gives answer.
Prevention CompletedThis study tested two different skin cleansers used before C-sections to see which one better prevents wound infections. About 1,400 women having a C-section at one hospital were randomly assigned to get either a 4% chlorhexidine water solution or a 2% chlorhexidine with alcohol …
Matched conditions: SURGICAL SITE INFECTION
Phase: PHASE4 • Sponsor: Hyagriv Simhan • Aim: Prevention
Last updated May 19, 2026 12:01 UTC
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Staples vs. glue: which closes colorectal surgery wounds better?
Symptom relief CompletedThis study looked at two ways to close the skin after colorectal cancer surgery: using metal staples or a special medical glue. The goal was to see which method leads to fewer wound infections and is more cost-effective. 304 adults who had planned colorectal surgery took part. Th…
Matched conditions: SURGICAL SITE INFECTION
Phase: NA • Sponsor: Yoon Suk Lee • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Can a simple nasal swab and cleansing routine stop joint surgery infections?
Knowledge-focused CompletedThis study looked at whether a special cleaning process (decolonization) for Staphylococcus aureus bacteria can lower the chance of infection after hip or knee replacement surgery. About 90 adults who tested positive for S. aureus in their nose took part. The main goal was to see…
Matched conditions: SURGICAL SITE INFECTION
Sponsor: Corporacion Parc Tauli • Aim: Knowledge-focused
Last updated May 26, 2026 08:34 UTC
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New software fights surgical infections by tracking hidden bacteria
Knowledge-focused CompletedThis study tested a software platform called OR PathTrac that tracks how bacteria spread during surgery. The goal was to help hospitals improve their cleaning and infection control steps to lower the risk of surgical site infections. Over 800 adults having surgery took part. The …
Matched conditions: SURGICAL SITE INFECTION
Sponsor: Georgetown University • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC