SUBSTANCE USE DISORDERS

This study tests a clinic-supported mobile health program called Connections for up to 806 HIV patients who also have substance use disorders. Participants get support from their care team and peer mentors for one year to help them stay virally suppressed and attend appointments.…

This study tests a program called the Bridge Model to help people who smoke and face challenges like homelessness or low income. The program offers support with jobs, housing, and social connections to help them quit tobacco and reduce substance use. Researchers will track change…

This study looks at two different approaches to help community hospitals start treating opioid use disorder. Researchers will compare a low-intensity and a high-intensity support strategy to see which one works better. The goal is to get more patients to start and stay on medicat…

This study aims to eliminate hepatitis C (HCV) among people who use drugs by offering free, community-based screening and immediate treatment in Paris, Marseille, Lyon, and Fort-de-France. About 3,400 participants will be tested and treated, and researchers will also study mental…

This study compares two approaches to help 208 adults with both substance use and mental health disorders: a team-based program called MISSION versus working one-on-one with a Peer Specialist. The goal is to see which method better reduces substance use, improves mental health, a…

This study tests whether remote sessions (via Zoom, phone, etc.) can help people with alcohol use disorder manage their drinking and improve well-being. About 300 participants will receive either a telehealth group program or standard care, and be followed for up to 12 months. Th…

This study tests a school program called PreVenture that helps teens understand their personality traits to avoid drug and alcohol problems. Over 12,000 10th graders across Canada will take part, with some schools using the program and others continuing their usual lessons. The g…

This small pilot study is testing whether a special type of drama therapy can help people who have both a mental health condition (like depression or bipolar disorder) and a substance use disorder. Ten participants will attend weekly group drama therapy sessions for 12 weeks and …

This early-stage study looks at whether psilocybin, the active ingredient in magic mushrooms, is safe and practical to use alongside behavioral support for people with methamphetamine use disorder. Twelve adults with the condition will receive two oral doses and be monitored for …

This study looks at how people's bodies react to stress in a pretend emergency room. Researchers will have 20 people who use meth and 10 healthy adults do public speaking and math tasks in a simulated ER. They will measure stress hormones, blood pressure, and heart rate to see if…

This study looks at different methods to help primary care clinics screen more adults for substance use problems. It involves 144 clinic staff from 48 practices. The methods include practice coaching, learning groups, and performance rewards. The goal is to see which approach wor…

This study looks at whether a text message-based mental health and substance use screening program helps more pregnant and postpartum women get the treatment they need compared to standard in-person screening. Over 10,000 women from MUSC clinics will participate by completing onl…

This study was designed to see if a brain training method called ZQLN could improve brain activity and thinking skills in people with cocaine use disorder. It planned to enroll adults aged 21 to 51 who had completed detox. However, the study was withdrawn before any participants …

This study tests a program to make substance use screening easier for people with HIV. It uses an online patient portal to screen patients, even if they don't have a clinic visit. The goal is to see if this approach increases screening rates and connects more people to treatment.

This study looks at how well a smartphone app works to help primary care clinics screen for and treat substance use disorders. About 60 adults who already have a primary care provider at Mayo Clinic will use the app to connect with care. The goal is to understand what helps or ge…

This study was designed to see if combining patient questionnaires, staff training, and telemedicine can help people living with HIV get better care for mental health and substance use issues. It planned to include adults receiving HIV care at five clinics in Alabama. The study w…

This study follows 120 people in group therapy for alcohol use disorders to see which patient traits—like mental health, drinking severity, personality, or thinking skills—lead to better outcomes. Researchers want to help doctors choose the right therapy for each person. The goal…