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ER stress study: can a fake waiting room reveal real reactions?

NCT ID NCT04317482

Knowledge-focused Sponsor: University of Arkansas Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how people's bodies react to stress in a pretend emergency room. Researchers will have 30 adults (20 who use meth and 10 healthy volunteers) do public speaking and math tasks while measuring stress hormones, heart rate, and blood pressure. The goal is to see if this setup feels like a real ER and to learn more about stress responses.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2020

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy adult * 21-55 years of age * Self-reported recent history of meth use that meets DSM-5 criteria for current meth use disorder * Have been previously inside an ED as either a patient or visitor * Able to construct a stressful mental script of ED experiences * Body mass index (BMI) \< 30 * Ability to read and understand English * If matched control, no lifetime history of any recreational or non-prescribed drug use. Exclusion Criteria: * Eating/drinking/taking drugs or alcohol the morning before the experiment * If smoker, not smoking the morning before the experiment * Subjective or objective signs of intoxication or withdrawal from any substance * History of any serious medical condition such as cardiovascular, endocrine, neurologic (seizures), or hepatic disease * Pregnancy * History of any mental illness * Hypertensive (\>150/90) or abnormal EKG at screening * Use of any daily medication * Any recent night shift work in the last 4 weeks * Any travel across time zones in the last 14 weeks * Participation in a similar study in the past year * Refusal to allow videotaping

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Conditions

The condition(s) this trial relates to.

Fractures, Stress methamphetamine dependence Stress, Psychological substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Methamphetamine-dependence Stress physiology Stress reaction Stress, emotional Substance use disorders

Contacts and locations

Locations

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

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