SUBSTANCE USE DISORDERS
Clinical trials for SUBSTANCE USE DISORDERS explained in plain language.
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New program aims to boost HIV care for people who inject drugs
Disease control CompletedThis study tested a program called iSTRIVE that combines emotional support and communication skills with video-checked medication reminders for people with HIV who also use opioids or stimulants. The goal was to see if this approach helps them stay engaged in HIV care and lower t…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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PrEP on wheels: HIV prevention delivered to those who need it most
Prevention CompletedThis study tested whether giving HIV prevention medicine (PrEP) right at a syringe exchange program helps people stay HIV-negative. 90 adults who were HIV-negative and used the syringe service took part. The goal was to see if offering PrEP on the spot improves adherence and redu…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: PHASE4 • Sponsor: University of Miami • Aim: Prevention
Last updated May 01, 2026 16:00 UTC
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Phone app helps former inmates access HIV prevention
Prevention CompletedThis study tested whether a GPS-based mobile app, financial incentives, and peer mentor support could help men who have sex with men and transgender women leaving jail get HIV prevention services like PrEP and testing. 233 participants were split into two groups: one received sta…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Prevention
Last updated Apr 28, 2026 13:02 UTC
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Learning life skills boosts confidence in recovery
Symptom relief CompletedThis study tested a life-skills training program in 45 men recovering from substance use disorders. The program aimed to improve their self-efficacy, or confidence in handling difficult situations. Participants completed a structured program after detoxification, and the study me…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 01, 2026 15:59 UTC
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Can online therapy and a buddy help beat addiction?
Symptom relief CompletedThis study looked at whether an online cognitive behavioral therapy program, called Breaking Free Online, helps people with substance use disorder cut back on their drug or alcohol use. About 198 adults from an outpatient addiction program took part. Some got standard care with g…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Symptom relief
Last updated May 01, 2026 15:59 UTC
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New telehealth therapy targets loneliness to curb substance use in veterans
Symptom relief CompletedThis study tested a cognitive-behavioral therapy (CBT) delivered via telehealth to help veterans who feel lonely and struggle with substance use. 36 veterans took part to see if the therapy was acceptable and helpful. The goal was to reduce loneliness and substance use, with resu…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Apr 30, 2026 15:49 UTC
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Phone support eases pain and substance risks for veterans
Symptom relief CompletedThis study tested a phone-based counseling program for veterans with chronic pain who were at risk for substance misuse. Over 1,100 veterans from New England took part. The program aimed to reduce pain and risky substance use by helping them access better pain treatment. Results …
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated Apr 30, 2026 15:48 UTC
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New therapy helps addicts tame emotions and cravings
Symptom relief CompletedThis study tested a short, 11-session therapy program for adults in residential rehab for drug or alcohol problems. The therapy combined techniques to improve emotion regulation, distress tolerance, and psychological flexibility. 36 participants were split into two groups: one re…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Lauro Gutiérrez Castro • Aim: Symptom relief
Last updated Apr 30, 2026 15:48 UTC
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Sleep therapy may boost recovery success for substance use patients
Symptom relief CompletedThis study looked at whether a short sleep program (Brief Behavioral Therapy for Insomnia) helps people living in a residential substance use treatment center sleep better and stay in recovery longer. About 83 adults took part, wearing sleep trackers and completing surveys. Resea…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 29, 2026 15:01 UTC
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Can a depression scale help understand substance use?
Knowledge-focused CompletedThis study checked if a questionnaire called the Behavioral Activation for Depression Scale (BADS) works well for people with substance use disorders. Researchers looked at answers from 289 adults to see if the scale is reliable and accurate. The goal was to improve how depressio…
Matched conditions: SUBSTANCE USE DISORDERS
Sponsor: Lauro Gutiérrez Castro • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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ER peer coaches may boost recovery linkage for substance use
Knowledge-focused CompletedThis study tested whether peer recovery coaches in the emergency department can help people with substance use disorders connect to treatment and support resources. 144 adults were split into three groups: in-person coaching, video call coaching, or just a list of resources. Rese…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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Can video coaching help families navigate psychosis and addiction?
Knowledge-focused CompletedThis pilot study tested a telehealth program called CRAFT-EP, designed to help families support a relative with early psychosis who also uses alcohol or cannabis. 65 family members participated to see if the program improved their well-being and reduced their own symptoms of depr…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC
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Who seeks addiction treatment? new study reveals key traits
Knowledge-focused CompletedThis study looked at 106 people admitted for addiction treatment at Assiut University Hospital. Researchers collected information on their personal background, drug use patterns, and personality traits. The goal was to better understand who is affected by substance use disorders …
Matched conditions: SUBSTANCE USE DISORDERS
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC
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New manual aims to fix clinical trial diversity gap
Knowledge-focused CompletedThis study asked 65 African American adults who use cocaine or other drugs for their ideas on how to make clinical trials more welcoming. The goal was to create a manual (I-DREM) that researchers can use to recruit and keep more Black participants in substance use studies. Partic…
Matched conditions: SUBSTANCE USE DISORDERS
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:49 UTC
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Scientists seek secret ingredients for better teen addiction treatment
Knowledge-focused CompletedThis study looked at 129 teens aged 12 to 18 with substance use disorders to find out which parts of treatment help them the most. Researchers measured drug and alcohol use and problem behaviors over a year. The goal is to make treatments more effective by focusing on what really…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Oregon Social Learning Center • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:48 UTC
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Mindfulness shows promise in addiction recovery, but relapse remains a challenge
Knowledge-focused CompletedThis small study looked at whether an 8-week mindfulness and meditation program could help people with substance use disorders stay sober. Three adults completed the program, and while they all felt less stressed and more mindful afterward, two had a relapse within a year. One pe…
Matched conditions: SUBSTANCE USE DISORDERS
Sponsor: Bout Me Healing • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:48 UTC
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New parenting support program shows promise for mothers in recovery
Knowledge-focused CompletedThis study tested a 6-session telehealth parenting program called THRIVE for mothers with substance use disorder and their young children. The goal was to see if offering this program in a pediatric clinic was practical and well-received. Nine mothers participated, and researcher…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Boston Medical Center • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:15 UTC
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Can training and policy changes reduce stigma in HIV care?
Knowledge-focused CompletedThis study worked with 51 healthcare staff at primary care clinics to test if education and policy changes could reduce stigma toward people who use drugs. The goal was to improve HIV prevention and care. Researchers measured changes in staff attitudes and intentions to help, and…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Wayne State University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC