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Can a VR avatar help people stay off opioids?

NCT ID NCT05908097

Symptom relief Sponsor: Indiana University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Sep 15, 2026 · Updated 4 times

Summary

This study tested whether a virtual reality experience where people see an avatar of their future self could help those in early recovery from opioid use disorder reduce drug use and stay abstinent. 104 participants were split into a VR group and a control group. Researchers measured opioid use, abstinence, and changes in future thinking over 30 days.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Virtual reality avatar intervention
What this could lead to
If it works, this could offer a new, non-drug tool to help people in early recovery from opioid use disorder stay on track.
What could go wrong
This is a small early-phase trial with 104 participants, so results may not apply to everyone. The VR effect may be short-lived or no better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

104 people

The number who actually took part.

Started

Apr 2023

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Abstinence between ≥14 days and ≤ 1 year * 18-60 years old * Verbal endorsement of commitment to recovery * Outpatient * Psychotropic drugs for SUD-comorbidity * Mu-Opioid drugs * Drug/alcohol abstinence ≥ 24 hours at the time of the study day visit * English comprehension Exclusion Criteria: * Unstable medical disorders * Outside the age range of 18-60 * Habitual drug use * Smell/taste disorders * Unstable psychiatric conditions * Extravagant/elaborate face tattoos

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Conditions

The condition(s) this trial relates to.

opiate dependence opioid abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid use Opioid-use disorder Substance use disorders

Contacts and locations

Locations

  • Indiana University School of Medicine - Goodman Hall

    Indianapolis, Indiana, 46202, United States

  • Serenity Lane Alcohol & Drug Treatment

    Coburg, Oregon, 97402, United States

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