SECONDARY ACUTE MYELOID LEUKEMIA
Clinical trials for SECONDARY ACUTE MYELOID LEUKEMIA explained in plain language.
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New antibody tested in fight against tough blood cancers
Disease control OngoingThis early-stage study is testing a new antibody drug called Hu8F4 in patients with advanced blood cancers like leukemia and myelodysplastic syndrome (MDS) that have not responded to other treatments. The main goals are to find the safest and most effective dose and to understand…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 04, 2026 02:06 UTC
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New radiation technique tested to prepare patients for Life-Saving stem cell transplants
Disease control TerminatedThis early-phase study is testing the safety and best dose of a targeted radiation treatment, given with two chemotherapy drugs, to prepare patients for a donor stem cell transplant. The goal is to better wipe out cancer cells in the bone marrow before receiving healthy donor cel…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 04, 2026 02:05 UTC
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New combo therapy aims to wipe out lingering leukemia cells in older patients
Disease control OngoingThis study is for older adults newly diagnosed with a type of blood cancer called acute myeloid leukemia (AML) who cannot or choose not to have intensive chemotherapy. It compares two treatment plans: the current standard two-drug combination versus adding a third immunotherapy d…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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Scientists test Triple-Threat drug attack on tough blood cancer
Disease control OngoingThis early-stage study is testing a new combination of three drugs—navtemadlin, decitabine, and venetoclax—for adults with acute myeloid leukemia (AML). The main goals are to find the safest dose and understand the side effects. The hope is that using all three drugs together wil…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Scientists test Immune-Boosting combo against tough blood cancers
Disease control OngoingThis early-stage study is testing the safety and best dose of a two-drug combination for patients with advanced myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) that has returned or not responded to prior treatment. The trial combines a chemotherapy drug (decitabine…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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Engineered immune cells target Tough-to-Treat leukemia in early trial
Disease control OngoingThis early-stage study is testing a new type of CAR T-cell therapy for adults with acute myeloid leukemia (AML) or a related blood cancer that has come back or not responded to other treatments. Doctors take a patient's or a donor's immune cells, genetically modify them to better…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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New hope for Tough-to-Treat leukemia: experimental drug combo enters testing
Disease control TerminatedThis study is testing whether adding a drug called venetoclax to a standard chemotherapy regimen (FLAG or CLAG) is more effective for treating newly diagnosed secondary acute myeloid leukemia (sAML). The main goal is to see if this combination helps more patients achieve complete…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New drug combo tested to fight leukemia in seniors
Disease control OngoingThis study tested a combination of two drugs, azacitidine and gemtuzumab ozogamicin, to treat older adults with a type of blood cancer called acute myeloid leukemia (AML). The goal was to see if this combination was safe and effective enough to put patients into remission and war…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New hope for AML patients: can a Cancer-Fighting drug boost Chemo's power?
Disease control OngoingThis study is testing if adding the immunotherapy drug pembrolizumab to standard chemotherapy works better for adults newly diagnosed with acute myeloid leukemia (AML). The goal is to see if the combination helps more patients achieve a deep remission with no detectable cancer ce…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New hope for tough leukemia in younger patients
Disease control OngoingThis study is testing how well a chemotherapy drug called CPX-351 works for adults under 60 with secondary acute myeloid leukemia, a type of blood cancer that develops from other blood disorders or previous cancer treatments. The goal is to see if this drug can help patients achi…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New strategy aims to tame dangerous virus after cancer transplant
Disease control OngoingThis study is testing a personalized plan to manage cytomegalovirus (CMV), a common and potentially serious infection, in patients who have received a donor stem cell transplant for blood cancers or disorders. The plan involves closely monitoring the virus level and the patient's…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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New strategy aims to make leukemia cells more vulnerable to chemo
Disease control OngoingThis study is testing whether adding a drug called decitabine before standard chemotherapy helps treat acute myeloid leukemia (AML) more effectively. The goal is to see if decitabine can 'prime' or sensitize the cancer cells, making them easier for the chemotherapy drugs to kill.…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 11, 2026 14:54 UTC
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Scientists test new drug cocktail in fight against tough blood cancer
Disease control OngoingThis early-stage study is testing a combination of three drugs—bortezomib, sorafenib, and decitabine—to treat acute myeloid leukemia (AML). The main goal is to find the safest and most effective dose. The study is for adults with AML who are older, have a type that is hard to tre…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 02, 2026 15:24 UTC
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Phone therapy trial aims to ease debilitating cancer fatigue
Symptom relief OngoingThis study is testing whether a type of talk therapy, delivered over the phone, can help patients with acute myeloid leukemia (AML) or lymphoma manage severe, long-lasting cancer-related fatigue. The therapy focuses on teaching patients skills to change unhelpful thoughts and beh…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Mar 12, 2026 13:50 UTC