New combo therapy aims to boost remission in tough leukemia cases
NCT ID NCT01627041
First seen Oct 31, 2025 · Last updated May 20, 2026 · Updated 31 times
Summary
This study tests whether adding a drug called decitabine to standard chemotherapy can improve remission rates in adults with acute myeloid leukemia (AML) that is harder to treat. About 178 participants will receive either low or high dose decitabine alongside chemo drugs daunorubicin and cytarabine. The goal is to see which dose works better at killing cancer cells and stopping the disease from coming back.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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Lafayette Family Cancer Center-EMMC
Brewer, Maine, 04412, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467, United States
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Montefiore Medical Center-Weiler Hospital
The Bronx, New York, 10461, United States
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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032, United States
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NYP/Weill Cornell Medical Center
New York, New York, 10065, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
Conditions
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