Experimental combo offers hope for tough blood cancers
NCT ID NCT02890329
First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 32 times
Summary
This early-stage study tests a combination of two drugs—ipilimumab, which boosts the immune system to attack cancer, and decitabine, a chemotherapy drug—in people whose myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) has returned or not responded to prior treatment. The main goal is to find the safest dose and check for side effects. About 54 adults with these hard-to-treat blood cancers will take part.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Northside Hospital
Atlanta, Georgia, 30342, United States
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Virginia Cancer Center
Charlottesville, Virginia, 22908, United States
Conditions
Explore the condition pages connected to this study.