Experimental combo aims to outsmart resistant blood cancers
NCT ID NCT02890329
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 31 times
Summary
This early-phase study tests a combination of two drugs—ipilimumab (an immunotherapy that helps the immune system attack cancer) and decitabine (a chemotherapy drug)—in adults with myelodysplastic syndrome or acute myeloid leukemia that has returned or not responded to prior treatments. The main goal is to find the safest dose of ipilimumab when given with decitabine. About 54 participants will be enrolled. This is not a cure; it aims to control the disease.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Northside Hospital
Atlanta, Georgia, 30342, United States
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UC San Diego Moores Cancer Center
La Jolla, California, 92093, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Virginia Cancer Center
Charlottesville, Virginia, 22908, United States
Conditions
Explore the condition pages connected to this study.