RESPIRATORY INSUFFICIENCY

This study is testing a new decision-making method for surgeons during large hernia repair operations. It uses real-time measurements of how easily a patient's lungs are working to help decide the safest way to close the abdominal wall. The main goal is to see if this approach re…

This study is testing if starting a breathing machine, called non-invasive ventilation (NIV), earlier than the current standard can help people with ALS. Researchers will use a prediction tool to identify patients at higher risk for breathing problems and randomly assign them to …

This study is testing whether using a specific sedative medication called dexmedetomidine early in treatment helps older patients on breathing machines survive and recover better. Researchers will compare it to a placebo in 300 patients aged 65 and older who are critically ill in…

This study is testing whether freezing the nerves around broken ribs (a procedure called cryoablation) helps reduce pain and improve breathing better than standard pain treatments. Researchers will compare the two approaches in 30 adults with multiple painful rib fractures. The g…

This study is testing a new, improved mask for non-invasive breathing support. Researchers want to see if this new mask helps people breathe more slowly and comfortably compared to their usual mask. About 60 adults who already use a breathing mask for respiratory failure will try…

This study aims to understand how different pressure settings on a breathing machine affect the lungs and breathing muscles of patients in the intensive care unit. Researchers will test three pressure levels on 25 patients who are on a specific type of ventilator support. The goa…