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Can inhaled sedation save money and improve outcomes for ventilated ICU patients?

NCT ID NCT07734350

Knowledge-focused Sponsor: Hospital H+ Queretaro Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This observational study looks at whether inhaled sedation with isoflurane is a more cost-effective option than intravenous propofol for mechanically ventilated adults in the intensive care unit. Researchers will compare total care costs, duration of ventilation, ICU length of stay, and side effects between the two sedation methods using electronic medical records. The study includes 400 adults who were on a ventilator for at least 24 hours and received one of the two sedation approaches.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
inhaled isoflurane sedation versus intravenous propofol
What this could lead to
If inhaled sedation proves more cost-effective, it could become a preferred option for sedating critically ill patients on ventilators, potentially reducing healthcare costs.
What could go wrong
This is a retrospective observational study, so it cannot prove cause and effect. Differences in patient groups or care practices may influence results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 400 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult critically ill patients admitted to the intensive care unit at Hospital H+ Querétaro who required invasive mechanical ventilation for at least 24 hours and received either inhaled sedation with isoflurane or continuous intravenous propofol sedation during ICU stay will be selected through retrospective review of electronic medical records

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * Admission to the intensive care unit at Hospital H+ Querétaro * Invasive mechanical ventilation for at least 24 hours * Receipt of inhaled sedation or continuous intravenous propofol sedation during ICU stay Exclusion Criteria: * Extracorporeal membrane oxygenation * Severe traumatic brain injury * Transfer to another hospital unit * Less than 24 hours of mechanical ventilation

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Conditions

The condition(s) this trial relates to.

Critical Illness respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Critical illness Mechanical ventilation Respiratory insufficiency

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.