RESPIRATORY INSUFFICIENCY

This study tests whether combining two types of breathing exercises can help people with ALS cough stronger and breathe easier. About 34 participants will practice lung volume recruitment and expiratory muscle strength training. The goal is to improve lung function, reduce shortn…

This study is testing a simple device with motion sensors placed on a child's chest and belly to measure how well their breathing is coordinated. The goal is to see if it can detect breathing problems early, even before they are obvious to doctors. About 20 children aged 28 days …

This study looks at whether combining two simple tests—one measuring breathing effort and another checking blood markers for inflammation and nutrition—can better predict when ICU patients are ready to come off a ventilator. Researchers will follow 105 adults to see if this combi…

This study compares three different facemasks used with a breathing machine (noninvasive ventilation) in 20 people whose lungs are not removing carbon dioxide well. The goal is to see which mask helps the diaphragm work less while clearing CO2 more effectively. Results will guide…

This study looks at whether patients in the ICU with severe breathing problems can safely keep eating or drinking before they need a breathing tube (intubation). Currently, patients are often kept fasting, but this can cause discomfort and malnutrition. The study will compare pat…

This large, ongoing study tests several treatments for patients with severe breathing failure (acute hypoxemic respiratory failure). It includes up to 6,250 adults in the ICU who need oxygen or a breathing machine. The goal is to find which treatments—like different ventilator se…

This early-stage trial tests whether a new method of giving muscle relaxants can help patients on breathing machines breathe on their own more safely. It involves 23 adults with severe breathing failure. The goal is to see if the approach is safe and feasible, not to cure or trea…