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Can a simple ventilator setting during surgery prevent breathing problems?

NCT ID NCT07613177

First seen Jun 11, 2026 · Last updated Jun 22, 2026 · Updated 3 times

Summary

This study will test whether using higher or standard pressure on a ventilator during surgery helps patients breathe better after waking up. About 360 adults having planned non-chest, non-heart surgery will be randomly assigned to one of two pressure levels. The main goal is to see how well their lungs oxygenate the blood once they are fully awake, using a simple oxygen measurement.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Moscow Multi-disciplinary Clinical Center "Kommunarka"

    Moscow, Moscow, 108814, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Positive end-expiratory pressure (PEEP) during mechanical ventilation

What this could lead to

If successful, this could help doctors choose the best ventilator settings during surgery to reduce breathing problems after surgery.

What could go wrong

This is an early-stage study that hasn't started recruiting yet. It focuses on a short-term oxygen measurement, not long-term outcomes, so the real-world benefit is uncertain.

Conditions

The condition(s) this trial relates to.

Hypoxia Postoperative Complications Pulmonary Atelectasis Respiratory Insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.