HYPOXEMIA

This study tests a new ventilator (INBENTUS VERSATILE) in 81 adults who need help breathing due to conditions like pneumonia, ARDS, or COPD. Participants will use the ventilator for 3 to 48 hours, and researchers will monitor for side effects and how well the machine works. The g…

This study tests two methods of giving oxygen to children aged 6-16 during a stomach scope procedure to see which better prevents dangerously low oxygen levels. About 30 children will receive oxygen either through a special mask or a nasal tube. The goal is to find a safer way to…

This study tests whether an inhaled medication called Treprostinil (Tyvaso) can help deliver more oxygen to the blood in people with COPD who have low oxygen levels. Ten adults aged 40 and older will use a nebulizer four times daily for four weeks. Researchers will use special MR…

This study tests a medical device called PIMUN to see if it can reduce the time preterm babies spend with low oxygen levels. About 20 infants born before 34 weeks and diagnosed with apnea of prematurity will take part. Each baby will be monitored for 48 hours with the device and …

This study tests whether a special airway device (COMBO Endoscopy Oropharyngeal Airway) combined with high-flow oxygen can prevent low oxygen levels in severely obese patients during sedated endoscopy. About 410 adults with a BMI of 35 or higher will be randomly assigned to recei…

This study tests whether a training program for hospital staff can improve how oxygen levels are managed in ICU patients on breathing machines. The goal is to keep oxygen saturation between 90-96% and reduce the time patients need a ventilator. About 3,600 adults in the ICU who n…

This study looks at whether giving extra oxygen during a 6-minute walk test helps people with chronic lung disease walk farther and feel better. About 114 adults with conditions like COPD or interstitial lung disease will do two walking tests—one with their usual oxygen and one w…

This study tests whether using a breathing mask (positive airway pressure) or extra carbon dioxide monitoring (capnometry) can reduce dangerous drops in oxygen levels during ERCP, a procedure to treat bile duct problems. About 288 adults will be randomly assigned to one of three …

This study looks at how medical oxygen is provided in six countries in Africa and Asia. Researchers will interview policymakers, health workers, and others to find out what works and what doesn't. The goal is to improve oxygen access for people with breathing problems like pneumo…

This study looks at whether pulse oximeters—the clips placed on fingers to measure oxygen levels—work equally well for children with different skin tones who have congenital heart disease. Researchers will enroll 92 children under 18 undergoing heart surgery and compare the oxime…

This study aims to see if a person's skin pigmentation affects how well a Masimo pulse oximeter measures oxygen levels. Researchers will compare readings from 152 adults with light and dark skin who are in the intensive care unit and have low oxygen levels. The goal is to ensure …