HYPOXEMIA

This trial is testing a new ventilator called INBENTUS VERSATILE in 81 adults who need help breathing. The study checks if the device is safe and works well for conditions like ARDS, pneumonia, and COPD. Participants will use the ventilator for 3 to 48 hours and be monitored unti…

This study tests a medical device called PIMUN to see if it can reduce the time preterm babies spend with low oxygen levels. About 20 infants born before 34 weeks who have apnea of prematurity will be randomly assigned to use the device for 48 hours or receive usual care. Researc…

This phase 2 trial is testing whether an inhaled drug called treprostinil (Tyvaso) can improve oxygen delivery in the lungs of people with COPD who have low blood oxygen. Ten adults will use the nebulizer four times daily for four weeks, starting at a low dose and increasing as t…

This study tests whether using a portable oxygen concentrator (a lightweight, battery-powered device) during walking or exercise helps people with interstitial lung disease (ILD) or COPD feel less breathless and be more active in their daily lives. Twenty-four participants will t…

This study tests whether using a breathing mask (positive airway pressure) or a special carbon dioxide monitor (capnometry) during ERCP can reduce the number of times patients' oxygen levels drop dangerously low. About 288 adults having ERCP with sedation will be randomly assigne…

This study tests whether a new device that combines a bite block, oxygen tube, and airway support can prevent dangerously low oxygen levels in severely obese patients during sedated endoscopy. About 410 adults with a BMI of 35 or higher will be randomly assigned to receive either…

This study looks at whether giving extra oxygen during a 6-minute walk test helps people with chronic lung disease walk farther and feel better. About 114 adults with conditions like COPD or interstitial lung disease will do two walking tests—one with their usual oxygen and one w…

This study looks at whether skin pigmentation affects how well Masimo pulse oximeters measure oxygen levels. Researchers will compare readings from 152 ICU patients with light and dark skin who have low oxygen levels. The goal is to see if the device works equally well for everyo…

This study tests whether training ICU staff to keep oxygen levels between 90-96% helps patients on breathing machines recover faster. Researchers will track how many days patients are free from the ventilator and how often dangerously low oxygen goes unnoticed. The goal is to imp…

This study looks at whether pulse oximeters—the clips placed on fingers to measure oxygen levels—work equally well for children with different skin tones who have congenital heart disease. Researchers will enroll 92 children under 18 undergoing heart surgery and compare the oxime…

This study looks at how medical oxygen programs work in six countries across Africa and Asia. Researchers will interview policymakers, health workers, and others to find out what helps or hinders oxygen access. The goal is to improve national and global policies, not to test a ne…