HYPOXEMIA

This study tests a new ventilator (INBENTUS VERSATILE) in 81 adults who need help breathing due to conditions like pneumonia, ARDS, or COPD. Participants will use the ventilator for 3 to 48 hours, and researchers will monitor for side effects and how well the machine works. The g…

This study tests two methods of giving oxygen to children aged 6-16 during a stomach scope procedure to see which better prevents dangerously low oxygen levels. About 30 children will receive oxygen either through a special mask or a nasal tube. The goal is to find a safer way to…

This study tests whether using a breathing mask (positive airway pressure) or a special carbon dioxide monitor (capnometry) during ERCP sedation can reduce the risk of dangerously low oxygen levels. About 288 adults having ERCP will be randomly assigned to one of three groups: br…

This study tests a medical device called PIMUN to see if it can reduce the time preterm babies spend with low oxygen levels. About 20 infants born before 34 weeks and diagnosed with apnea of prematurity will take part. Each baby will be monitored for 48 hours with the device and …

This study tests whether an inhaled medication called Treprostinil (Tyvaso) can help people with COPD who have low blood oxygen levels. Ten adults aged 40 and older will use the Tyvaso nebulizer four times daily for four weeks. Researchers will use special MRI scans and breathing…

This study tests whether a new device that combines an airway tube, oxygen, and monitoring can reduce low oxygen levels during sedated endoscopy in people with severe obesity (BMI 35 or higher). About 410 participants will be randomly assigned to receive either standard high-flow…

This study looks at how medical oxygen is provided in six countries in Africa and Asia. Researchers will interview policymakers, healthcare workers, and others to understand challenges and find solutions. The goal is to improve oxygen access for patients with conditions like pneu…

This study tests whether training ICU staff to keep oxygen levels in a specific range (90-96%) helps patients on breathing machines. Researchers will track how many days patients are free from the ventilator and how often dangerously low oxygen goes unnoticed. The goal is to impr…

This study looks at whether pulse oximeters—the clips placed on fingers to measure oxygen levels—work equally well for children with different skin tones who have congenital heart disease. Researchers will enroll 92 children under 18 undergoing heart surgery and compare the oxime…

This study aims to see if a person's skin pigmentation affects how well a Masimo pulse oximeter measures oxygen levels. Researchers will compare readings from 152 adults with light and dark skin who are in the intensive care unit and have low oxygen levels. The goal is to ensure …

This study looks at whether giving extra oxygen during a 6-minute walk test helps people with chronic lung disease walk farther and feel better. About 114 adults with conditions like COPD or lung scarring will do two walking tests—one with their usual oxygen and one with extra ox…