RESPIRATORY FAILURE

This study tests a computer program that gives real-time feedback to doctors and nurses to help them set ventilators in a way that protects the lungs of critically ill patients. The goal is to see if this approach helps more patients receive lung-protective ventilation, which can…

This study tests a new breathing device called Biphasic Cuirass Ventilation (BCV) against standard non-invasive ventilation in 50 high-risk patients who are being taken off a mechanical ventilator. The goal is to see if BCV can reduce the need for re-intubation. Participants are …

This study tests two methods to strengthen breathing muscles in patients with respiratory failure who are on a ventilator. One method slowly increases the effort needed to trigger a breath, while the other gradually lowers the breathing support. The goal is to see which approach …

This study tests whether an improved non-invasive ventilation (NIV) mask can lower how often people need to breathe compared to a standard mask. About 60 adults who already use NIV for respiratory problems will try both masks for one hour each. Researchers will measure breathing …

This study tests a procedure called cryoablation, which uses cold to temporarily freeze nerves around broken ribs. The goal is to reduce severe pain, improve breathing, and prevent complications like pneumonia. About 30 adults with multiple rib fractures will be randomly assigned…

This study will observe 1,200 adults admitted to hospital resuscitation rooms in France. Researchers want to see if patients who go directly to the resuscitation room are less likely to need intensive care within 24 hours compared to those who are admitted later from the emergenc…

This study looks at whether the natural variation in heartbeats (heart rate variability) can signal when a patient on high-flow oxygen therapy needs a flow adjustment. Researchers will gradually lower the oxygen flow in 20 adults already on this breathing support and monitor thei…

This study looks back at 50 ICU patients with respiratory failure to see if a chest CT scan finds anything new that a simple chest X-ray missed. Moving critically ill patients for a CT scan can be risky and costly. The goal is to find out how often the CT actually changes treatme…

This study looks at how different levels of pressure from a breathing machine (ventilator) affect the lungs and diaphragm in 25 ICU patients with respiratory failure. Each patient will try three pressure settings to see which one helps them breathe more efficiently and with less …

This study tests whether a bedside lung ultrasound can help doctors see how well collapsed lung areas reopen in obese patients on breathing machines. About 45 adults with a BMI of 33 or higher will be scanned before, during, and after a standard lung-opening procedure. The goal i…