RESPIRATORY FAILURE

This study looked at whether giving inhaled heparin to COVID-19 patients on breathing machines could help them recover faster and survive. Researchers combined data from several smaller trials in Australia, Ireland, the US, and the UK. A total of 57 adults in intensive care took …

This study tested two ways of using a breathing machine during heart surgery that requires a heart-lung machine. One group received no breaths during that time, while the other received small, gentle breaths. The goal was to see which approach better prevents serious lung complic…

This study tested whether a computer-driven system (Smartcare/PS) could shorten the time children spend on a breathing machine compared to standard care. Thirty children with respiratory failure took part. The goal was to see if the computer could help them start breathing on the…

This study tested whether a newer breathing machine method (NAVA) helps patients with respiratory failure come off the ventilator faster than the usual method (PSV). 47 adults who had trouble weaning from ventilation were randomly assigned to one of the two methods. The goal was …

This study looked at whether taking L-arginine and liposomal vitamin C supplements could help reduce fatigue in people with COPD and chronic respiratory failure after completing a pulmonary rehabilitation program. The study involved 101 participants aged 40 to 90. The goal was to…

This study tested whether adding a second nerve block (rectus sheath block) to a standard chest wall block (pectointercostal fascial plane block) could better control pain after heart surgery. 62 adults having planned heart surgery through a breastbone incision were enrolled. The…

This study tested whether critically ill patients on breathing machines could safely manage their own sedation using a button-controlled device, instead of relying solely on nurses. 161 participants were randomly assigned to either self-manage their sedation or receive standard n…

This study examined whether using a checklist before placing a breathing tube in intensive care unit (ICU) patients reduces complications. Researchers compared intubation events before and after checklist use in 60 critically ill adults. The main focus was on preventing dangerous…

This study looked at 600 adults with severe COVID-19 lung failure who were treated with high-flow nasal oxygen and placed on their stomachs while awake. The goal was to see if this combination could reduce the need for a breathing tube and lower death rates. Researchers also want…

This study looked at 77 ICU patients on breathing machines who needed a tracheostomy (a tube placed in the windpipe to help breathing). Doctors used either a tiny camera (bronchoscopy) or ultrasound to guide the procedure. The goal was to see how each method affected patients' br…

This study looked at whether three blood test ratios (lactate-to-albumin, CRP-to-albumin, and procalcitonin-to-albumin) can predict the risk of death in critically ill adults in the ICU. Researchers reviewed medical records of 212 patients admitted to an ICU in 2024. The goal was…

This study looked at whether measuring tiny brain signals during a breathing test can help predict if a patient in the intensive care unit will successfully come off a breathing tube. Researchers monitored 70 intubated patients as they breathed on their own for a short trial. The…

This study looked at 24 critically ill adults on breathing machines (ventilators) to see if a simple tool called Pressure Muscle Index (PMI) could accurately measure how hard they were working to breathe. Researchers compared PMI to the current best method, which uses a small tub…

This study looked at 28 critically ill patients on breathing machines to see if an ultrasound of the diaphragm could detect a specific breathing problem called double triggering asynchrony. Researchers compared ultrasound results to standard ventilator readings. The goal was to f…

This study looked at whether lying face down (prone position) while awake can improve how air moves through the lungs in COVID-19 patients with breathing failure. Twenty adults with COVID-19 and low oxygen levels were monitored using a special imaging technique. The goal was to s…

This study looked at 48 ICU patients on breathing machines to understand how doctors can safely reopen collapsed parts of the lung. Researchers used a special gas analyzer to measure lung volume before and after a brief high-pressure breath. The goal was to find out which measure…

This study looked back at the medical records of 250 COVID-19 patients who needed breathing support with a CPAP machine. The goal was to see how well this treatment worked in real life and track outcomes like survival and need for a breathing tube. No new treatments were tested; …

This study tested three common ways to set a breathing machine (ventilator) for critically ill adults with respiratory failure. The goal was to see if the choice of mode affects how many days patients are alive and off the ventilator. 566 patients took part across multiple ICUs. …

This small pilot study tested whether it is possible to set personalized blood pressure targets for critically ill patients based on their brain's oxygen levels. Researchers monitored 16 ICU patients with respiratory failure or shock for 24 hours to find each patient's optimal bl…