RADIOTHERAPY

This study tests whether adding a special type of radiation (quad shot radiotherapy) to a drug called QL1706 (which boosts the immune system) plus standard chemotherapy can better control advanced non-small cell lung cancer. About 104 people with stage IV lung cancer that has not…

This study tests whether a single, low dose of radiation to all visible tumors can help immunotherapy work again in people with advanced esophageal cancer that stopped responding to standard treatment. About 32 adults will receive the radiation and continue their current immunoth…

This study tests whether a short course of radiation, while keeping certain lymph nodes intact, followed by an immunotherapy drug (PD-1 inhibitor) can completely eliminate rectal cancer before surgery. It involves 44 adults with stage II-III rectal cancer. The goal is to see if t…

This study tests whether a combination of PRaG-1 tablets (made from a natural fungus), targeted radiation, immune-boosting shots, and immunotherapy can help people with advanced solid tumors that have not responded to standard treatments. About 65 participants will receive all tr…

This early-phase study tests whether giving a precise, low dose of radiation to the center of a lung tumor can 'prime' the immune system before standard chemoradiation and immunotherapy. About 24 adults with advanced, inoperable lung cancer will receive this experimental radiatio…

This study looks at people with stage IV non-small cell lung cancer that has spread to many places (more than 5 spots). It tests whether adding high-dose radiation to the main lung tumor, along with standard drug therapy, can help them live longer or keep the cancer from growing.…

This study tests a new treatment for people with extensive-stage small cell lung cancer, a fast-growing cancer that has spread. The approach combines low-dose radiation to the chest with chemotherapy and an immunotherapy drug (adebrelimab), followed by maintenance immunotherapy f…

This study looks at whether giving radiation therapy after surgery can help prevent cancer from returning in people with high-risk adrenocortical carcinoma, a rare adrenal gland cancer. About 58 patients who had their tumor completely removed will be randomly assigned to either r…

This study tests a chemotherapy drug (TAS-102) combined with radiation in people aged 65–85 with advanced esophageal cancer. The goal is to find the best dose and see if the combination helps patients live longer. About 45 participants will receive the treatment, followed by a re…

This study looks at whether a supervised, moderate-intensity interval walking program can reduce inflammation, improve physical fitness, and enhance quality of life in women with breast cancer who are undergoing radiotherapy. Forty women aged 20-65 with early-stage breast cancer …

This study looks at whether listening to calming music during the first radiation session can lower anxiety, stress, and pain in cancer patients. About 72 adults starting radiation will be split into two groups: one gets standard care, the other also hears 15-20 minutes of medita…

This study tests a new device called eMotus that tracks a patient's breathing movements during radiation therapy for cancers in the chest or upper abdomen. The goal is to see if this system can accurately guide the radiation beam without needing a backup method. About 20 adults w…

This study looks at whether giving radiotherapy after surgery for spinal metastases (cancer that has spread to the spine) helps patients live longer or have better outcomes. Researchers will follow 130 adults who have already had surgery to compare those who receive radiotherapy …

This study tests whether using MRI scans to plan radiotherapy is better than using CT scans alone. Researchers will work with up to 150 cancer patients and 15 healthy volunteers to see if MRI can make treatment more precise and reduce side effects. The goal is to improve how doct…