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MRI vs. CT: new study aims to sharpen cancer radiotherapy

NCT ID NCT07365124

Knowledge-focused Sponsor: Swansea Bay University Health Board Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using MRI scans to plan radiotherapy is better than using CT scans alone. Researchers will work with up to 150 cancer patients and 15 healthy volunteers to see if MRI can make treatment more precise and reduce side effects. The goal is to improve how tumors are targeted and to find MRI markers that predict treatment response.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 165 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Jan 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The participants for this study will be: 1. healthy volunteers from Swansea Bay University Health Board or Swansea University 2. patients with cancer who are due to undergo radiotherapy at Swansea Bay University Health Board

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for health volunteers: * Free from medical conditions that could confound imaging or study results * Eligible for MRI Inclusion Criteria for patients: * Confirmed diagnosis of invasive carcinoma at the relevant tumour/target sites listed in this protocol * Scheduled to receive radiotherapy to the target site * ECOG performance status of 0-2 * Eligible for MRI (determined through MRI safety screening) Exclusion Criteria: * Presence of medical conditions that may interfere with study outcomes or data interpretation * Use of regular medications that could affect imaging results or safety * Any contraindications to MRI scanning, including but not limited to claustrophobia, reduced thermal regulatory capabilities, MR Unsafe implants and foreign bodies.

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Conditions

The condition(s) this trial relates to.

brain cancer carcinoma carcinoma of esophagus Esophageal Neoplasms exocrine pancreatic carcinoma gastric cancer gastric neoplasm glioblastoma neoplasm nervous system cancer Neurologic Manifestations pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain (nervous system) cancers Carcinoma Gastric cancer Glioblastoma MRI Mri image enhancement Mri scanner configuration Mri-guided adaptive radiotherapy Oesophageal carcinoma Pancreas carcinoma Radiotherapy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Swansea Bay University Health Board

    Swansea, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.