PULPITIS
Clinical trials for PULPITIS explained in plain language.
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New tooth-saving technique matches root canal success in study
Disease control CompletedThis study compared two ways to treat badly inflamed tooth pulp: a newer method called vital pulp therapy (VPT) and the standard root canal treatment (RCT). 43 adults with painful, deep cavities took part and were followed for one year. Both treatments aimed to save the tooth and…
Matched conditions: PULPITIS
Phase: NA • Sponsor: Universidad Central de Venezuela • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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Could a simple pill replace the drill for toothache emergencies?
Symptom relief CompletedThis study compared an oral steroid (prednisolone) to a partial root canal for relieving severe tooth pain from pulpitis. Only 5 adults with a painful lower molar took part. The goal was to see if the pill could reduce pain enough to delay the full root canal by 72 hours, potenti…
Matched conditions: PULPITIS
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 24, 2026 02:32 UTC
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Light therapy may ease root canal pain, small study suggests
Symptom relief CompletedThis study tested whether photodynamic therapy (PDT) — a light-based treatment — can reduce pain after root canal treatment. 95 adults with pulpitis (tooth nerve inflammation) received either standard cleaning or PDT-enhanced cleaning. Researchers measured pain levels and painkil…
Matched conditions: PULPITIS
Sponsor: Atlas University • Aim: Symptom relief
Last updated Jun 22, 2026 11:58 UTC
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AI helps dentists spot hidden infections – could save more teeth from root canals?
Symptom relief CompletedThis study tested a procedure called full pulpotomy (removing only the infected pulp inside the tooth crown) in 58 adults with severe toothache. It compared success in teeth with and without an infection at the root tip (apical periodontitis), using an AI tool to help detect the …
Matched conditions: PULPITIS
Phase: NA • Sponsor: Misr International University • Aim: Symptom relief
Last updated Jun 17, 2026 12:08 UTC
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Cold therapy may ease pain after root canal, study finds
Symptom relief CompletedThis study tested whether applying cold (cryotherapy) during pulpotomy or root canal treatment reduces pain and improves quality of life. 144 adults with deep cavities in their molars were randomly assigned to receive either standard treatment or treatment with added cryotherapy.…
Matched conditions: PULPITIS
Phase: NA • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 09, 2026 12:08 UTC
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Scientists decode the hidden chemistry of tooth pain and anxiety
Knowledge-focused CompletedThis study looked at 72 adults to see how certain nerve chemicals (substance P and CGRP) in saliva and tooth pulp relate to dental pain, inflammation, and psychological stress. Participants provided saliva samples and had their pain levels and mental health assessed. The goal was…
Matched conditions: PULPITIS
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:08 UTC
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Tooth inflammation biomarkers measured in new study
Knowledge-focused CompletedThis study looked at 51 people to compare levels of three substances (IL-8, FGF-1, and VEGF) in teeth that are healthy, mildly inflamed, or severely inflamed. Samples were taken from the tooth pulp, gum fluid, and dentin fluid during routine root canal treatment. The goal was to …
Matched conditions: PULPITIS
Sponsor: Kırıkkale University • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:08 UTC