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Could a simple pill replace the drill for toothache emergencies?

NCT ID NCT02629042

First seen May 12, 2026 · Last updated Jun 23, 2026 · Updated 10 times

Summary

This study compared an oral steroid (prednisolone) to a partial root canal for relieving severe tooth pain from pulpitis. Only 5 adults with a painful lower molar took part. The goal was to see if the pill could reduce pain enough to delay the full root canal by 72 hours, potentially making the procedure less painful and more convenient.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU de Bordeaux

    Bordeaux, 33000, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

prednisolone

What this could lead to

If it works, this could offer a simpler, less painful way to manage severe toothache before a full root canal.

What could go wrong

This was a very small trial (only 5 participants) and results may not apply to everyone. The drug may not control pain as well as the standard procedure.

Conditions

The condition(s) this trial relates to.

agnosia pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.