PULPITIS

This study compares different numbing methods to reduce pain during dental cavity treatment. About 204 adults with tooth decay will receive either a light-based device, a numbing gel, or a placebo before local anesthesia. Researchers will measure pain during and after the procedu…

This study tests four different ways to clean infected root canals to see which one reduces bacteria and pain the most. Forty adults with tooth infections will be randomly assigned to one of the cleaning methods. The goal is to find a better way to disinfect teeth while making th…

This study will follow 75 adults who need a root canal or a repeat root canal at a hospital dental clinic. Researchers will check for healing, pain, and tooth survival over up to 5 years. The goal is to understand success rates and how overall health might affect outcomes.

This study looks at whether simple saliva and gum fluid tests can detect inflammation inside the tooth. Researchers will compare 50 people with painful tooth nerve inflammation to healthy volunteers. The goal is to find non-invasive ways to diagnose and monitor pulpitis without r…

This study looks at certain proteins (aquaporins and IL-8) in the fluid and tissue of healthy teeth and teeth with a painful, inflamed nerve (irreversible pulpitis). Researchers will collect samples from 70 adults during routine root canal treatment to compare protein levels. The…