New study tests light and gel to ease dental pain
NCT ID NCT07379515
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares different numbing methods to reduce pain during dental cavity treatment. About 204 adults with tooth decay will receive either a light-based device, a numbing gel, or a placebo before local anesthesia. Researchers will measure pain during and after the procedure to find the best approach for patient comfort.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Photobiomodulation device and benzocaine 20% gel
- What this could lead to
- If successful, this could give dentists a better way to numb teeth before cavity treatment, reducing pain and improving the dental experience.
- What could go wrong
- This is a small, early-stage trial with only 204 participants. Results may not apply to all patients or dental procedures, and the device or gel may not work better than placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 204 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 59 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy participants: American Society of Anesthesiology Class I or II * Adults aged 18-59 years * No history of allergy to local anesthesia or excipients included in the vial * Participant requiring caries management for a maxillary premolar tooth (ICDAS I-V), with reversible pulpitis. Exclusion Criteria: * American Society of Anesthesiology Class III or higher * Participants with systemic conditions affecting pain perception * Participants on chronic pain medication * Pregnant or breastfeeding women * History of allergy to topical/local anesthesia * Taking any analgesic 48 hours before testing, such as an NSAID, opioids, or * acetaminophen * Recent oral trauma * Deep carious lesion with irreversible pulpitis or pulpal necrosis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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