PSORIATIC ARTHRITIS

This study tested two drugs, secukinumab and ustekinumab, in 119 adults with active psoriatic arthritis who had not responded to or could not tolerate TNFα-inhibitor treatments. The goal was to see which drug better improves physical function and skin symptoms over 28 weeks. Part…

This study tested a daily pill called upadacitinib in 642 adults with active psoriatic arthritis who had not gotten enough relief from biologic drugs. Participants received either 15 mg, 30 mg of upadacitinib, or a placebo for 12 weeks. The main goal was to see if the drug reduce…

This study tested a new medicine called bimekizumab in 852 adults with active psoriatic arthritis, a condition causing joint pain and swelling. Participants received either bimekizumab, a placebo (inactive shot), or an existing drug (adalimumab) to compare effectiveness and safet…

This study tested three different treatment strategies for people newly diagnosed with moderate to severe psoriatic arthritis. One group received standard care, another got a combination of disease-modifying drugs early on, and the third started with a stronger biologic drug (TNF…

This study tested a drug called bimekizumab in 400 adults with active psoriatic arthritis who had not responded well to standard TNF-blocking treatments. The goal was to see if bimekizumab could reduce joint pain and swelling better than a placebo. Participants received injection…

This study followed 116 adults with moderate to severe psoriatic arthritis who were starting tofacitinib as part of their normal care. Researchers tracked disease activity, remission rates, and quality of life over 12 months. The goal was to see how well the drug works in real-wo…

This study looked at how safe and effective the drug risankizumab (brand name Skyrizi) is for adults with moderate to severe plaque psoriasis or psoriatic arthritis. Over 2,300 participants in Korea received the drug as prescribed by their doctor for 52 weeks. Researchers tracked…

This study tested a new drug called bimekizumab in 567 adults with moderate to severe plaque psoriasis. The goal was to see if it could clear skin better than a placebo or an existing treatment. Participants received injections and were monitored for improvement in skin redness, …

This study tested whether adding golimumab to methotrexate works better than methotrexate alone for people with very early psoriatic arthritis (PsA). 84 adults with active PsA diagnosed within the last 2 years took part. The main goal was to see if the combination reduced disease…

This study tested a higher dose (10 mg/kg every 8 weeks) of the drug TA-650 in 51 adults with psoriasis whose symptoms had returned after initially responding to the standard dose of Remicade. The goal was to see if the increased dose could again improve skin symptoms, as measure…

This study tested whether adding a weight-loss drug (tirzepatide) to a standard psoriatic arthritis treatment (ixekizumab) helps people with both active psoriatic arthritis and obesity or overweight. About 279 adults took part, receiving either ixekizumab alone or both drugs toge…

This study tested whether people with rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis could switch from receiving infliximab through an IV drip at the hospital to giving themselves a simple shot under the skin at home. 22 adults who were already stable on IV …

This study tested a drug called bimekizumab against a placebo in 435 adults with moderate to severe plaque psoriasis. The goal was to see if the drug could clear or nearly clear skin patches. Results showed significant improvement in skin symptoms for those taking bimekizumab.

This study followed 76 adults who had shoulder replacement surgery with the MIRAI prosthesis to see how well the implant worked over 5 years. Researchers measured shoulder function, movement, and implant stability, and tracked any complications. The goal was to understand the ben…

This study tested a daily pill called upadacitinib in 1,705 adults with active psoriatic arthritis who had not gotten enough relief from standard non-biologic drugs. The goal was to see if it reduced joint pain and swelling better than a placebo or an injected biologic (adalimuma…

This study tested whether structured telemedicine visits that encourage lifestyle changes can improve quality of life and reduce disease activity in people with psoriatic arthritis. 101 adults with active symptoms took part. Researchers measured satisfaction, disease impact, and …

This study involved 324 adults with conditions like Crohn's disease, arthritis, or psoriasis who switched from a standard to a higher-concentration adalimumab injection. Researchers measured injection site pain and how well patients stuck with the new treatment over 180 days. The…

This study looked at whether intermittent fasting (eating only during certain hours) can reduce disease severity and improve quality of life for people with psoriasis and psoriatic arthritis. Sixty overweight adults were randomly assigned to either follow an intermittent fasting …

This study looked at fatigue in 33 adults with psoriatic arthritis or psoriasis. Researchers used questionnaires to compare tiredness levels and see how treatments and disease severity play a role. The goal was to better understand fatigue, a common but often overlooked symptom.

This study looked at 86 people with rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis to see if air pollution triggers flare-ups. Participants reported their symptoms weekly for 6 months, while researchers measured their exposure to pollutants based on where th…

This study tested whether a non-invasive ultrasound device can reduce inflammation in people with psoriatic arthritis, rheumatoid arthritis, or ankylosing spondylitis. Sixteen participants received four ultrasound sessions, one of which was a sham (placebo). The main goal was to …

This study aimed to create and test a patient decision aid—a tool to help people with psoriasis or psoriatic arthritis work with their doctors to choose a new treatment. Researchers worked with 37 patients and providers to design and evaluate the aid. The goal was to improve shar…

This study looked at nearly 7,000 adults with inflammatory joint diseases like rheumatoid arthritis and ankylosing spondylitis. Researchers compared two versions of a health questionnaire (EQ-5D-3L and EQ-5D-5L) to see which one better measures quality of life and disease activit…

This study followed 127 adults with moderate to severe plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, or non-radiographic axial spondyloarthritis for 2 years. Researchers collected real-life data on how long patients stayed on secukinumab treatment and how their q…

This study looked at 70 adults with psoriatic arthritis to compare two types of drugs—upadacitinib and IL-17 inhibitors—in everyday medical practice. Researchers tracked joint and skin symptoms over 24 weeks to see which treatment worked better. The goal is to help doctors and pa…

This study looked at the safety of the drug abatacept in over 140,000 people with rheumatoid arthritis or psoriatic arthritis in Sweden. Researchers tracked how many people developed different types of cancer while taking abatacept or other arthritis medications. The goal was to …