PREECLAMPSIA

This study looks at whether giving blood pressure medicine (enalapril) to women who had preeclampsia or high blood pressure during pregnancy can help their heart health after childbirth. Researchers will enroll 60 postpartum women to see if they are willing to take the medicine a…

This study tests two types of progestin-only birth control pills (drospirenone and norethindrone) to see which one helps control high blood pressure better in women who had preeclampsia during pregnancy. About 50 participants will take one of the pills for 6 weeks after leaving t…

This study tests a drug called topefilgrastim in 100 pregnant women at high risk for preeclampsia, a serious condition causing high blood pressure. Participants receive either a low or high dose of the drug or standard care. The goal is to see if the drug can lower harmful protei…

This study will test whether taking a daily vitamin D supplement (2,000 IU) during pregnancy can prevent preeclampsia, eclampsia, and HELLP syndrome in about 1,980 pregnant women in Uganda. Participants will receive either vitamin D or a placebo from their first visit until deliv…

This study tests a personalized support program (PTBCARE+) for pregnant individuals at high risk of delivering early. The program includes stress-reduction tools, a website/app, and extra support during clinic visits. Researchers will compare stress levels and birth outcomes betw…

This study tests whether taking progesterone (a natural hormone) early in pregnancy can prevent preeclampsia, a serious condition causing high blood pressure. About 642 low-risk pregnant women will either receive nightly vaginal progesterone or standard care. The goal is to see i…

This study tests whether mindfulness training, with or without wearable biosensors, can help prevent preeclampsia in pregnant women at moderate to high risk. 90 women will be randomly assigned to one of three groups: mindfulness plus biosensors, mindfulness alone, or standard pre…

This study compares stretching exercises to aerobic exercises for women with mild preeclampsia. Sixty first-time pregnant women, aged 20-30, will do one type of exercise for six weeks. Researchers will measure changes in blood pressure and protein in urine to see which exercise h…

This study tests whether a quick, non-invasive bedside ultrasound can help doctors decide if new mothers with preeclampsia need a diuretic (water pill) to lower their blood pressure. About 96 postpartum women with preeclampsia will receive ultrasound-guided treatment within 24 ho…

This study aims to understand what causes preeclampsia, a dangerous pregnancy condition. Researchers will measure a protein called sFlt1 in the blood of 500 women, including healthy pregnant women and those with preeclampsia. The goal is to find better ways to diagnose and treat …

This study looks at whether a simple neck ultrasound can predict a sudden drop in blood pressure during a C-section in women with preeclampsia. Researchers will measure the jugular vein collapsibility before spinal anesthesia and track blood pressure changes afterward. The goal i…

This study will follow 1300 women with type 1 diabetes to see if a high risk of preeclampsia in early pregnancy is linked to heart disease and other health problems years later. Researchers will check for plaque in neck arteries, blood sugar control, and heart events. The goal is…

This study checks if a formula called fullPIERS can accurately predict which pregnant women with preeclampsia (high blood pressure and protein in urine) will have serious health problems. Researchers will collect medical information from 50 women within 48 hours of admission to s…

This study will look at 120 pregnant women with high blood pressure to see if certain ultrasound scans and blood tests can predict who will develop severe preeclampsia. The goal is to find better ways to identify women at highest risk for serious complications for both mother and…

This study looks at whether expressing breastmilk during pregnancy (from week 28) is safe for women at high risk of preterm birth. It involves 250 pregnant women with conditions like preeclampsia or a history of early delivery. Researchers will measure how long until delivery, ho…

This study looks at a natural chemical called kynurenine in pregnant women with and without chronic kidney disease. Researchers want to see if low levels of this chemical are linked to preeclampsia, a dangerous condition that can harm mothers and babies. About 200 women will give…