POSTOPERATIVE PAIN, ACUTE

This study aims to find the ideal dose of spinal morphine to control pain after a C-section. Researchers will test different doses in 100 healthy women having planned C-sections, adjusting the dose based on each woman's pain relief. The goal is to keep pain scores low for at leas…

This study compares a long-acting numbing medicine (liposomal bupivacaine) to a standard one for pain after lung surgery. About 210 adults having keyhole lung surgery will be randomly assigned to receive one of the two drugs or no nerve block. The goal is to see if the long-actin…

This study tests two different remote support programs to see which one helps women feel better after surgery for suspected gynecological cancer. About 160 women will take part, and researchers will measure pain, mood, and sleep. The goal is to find the best way to improve recove…

This study looks at whether giving the painkiller nalbuphine at different times during knee replacement surgery can better control pain and keep the heart and blood pressure stable in patients aged 65 and older. About 162 participants will receive the same dose of nalbuphine but …

This study tests a new extended-release painkiller called PF614 for people with moderate to severe pain after tummy tuck surgery. About 320 adults will take the drug or a placebo before surgery and every 12 hours for up to 4 days. Researchers will measure pain levels, need for ex…

This study tests if a specific nerve block (SPSIP block) can reduce pain and the need for strong painkillers after shoulder surgery. About 80 adults having arthroscopic shoulder surgery will either get the nerve block or standard care. The main goal is to see if the block lowers …

This study tests whether giving the painkiller ketorolac directly into a leg (after a tourniquet is tightened) during lower limb orthopedic surgery can extend pain relief after the operation. About 76 adults having elective leg surgery under spinal anesthesia will be randomly ass…

This study looks at whether a single dose of meloxicam (a pain reliever) can control pain better than the usual ibuprofen after Mohs surgery for skin cancer. About 300 adults will be split into three groups: one gets a low dose of meloxicam, one gets a higher dose, and one gets s…

This study tests if a special numbing injection (nerve block) can reduce pain and the need for strong painkillers after ear surgery in teenagers aged 13 to 18. Half of the 60 participants will get the injection before surgery, and the other half will not. The main goal is to see …

This study tests whether a special nerve block (PENG block) given before hip replacement surgery can help patients have less pain, use fewer strong painkillers, and get out of bed and walk sooner. The study will include 60 adults between 40 and 85 years old who are having hip rep…

This study compares two types of nerve blocks to prevent chronic pain after video-assisted lung surgery. Forty adults scheduled for elective lung surgery will be randomly assigned to receive either an ultrasound-guided nerve block or a surgeon-given block. The goal is to see whic…