ORAL CANCER

This study is testing whether antibiotics and a special mouthwash can reduce bacteria inside oral cancer tumors before surgery. Researchers want to see if lowering bacteria levels changes the tumor environment and might improve treatment outcomes. The study involves 30 adults wit…

This study is testing if using an ultrasound machine during surgery helps surgeons remove oral cancer more completely. About 200 patients will be randomly assigned to have standard surgery or surgery guided by real-time ultrasound images. The goal is to see if the ultrasound help…

This study is testing a new, personalized treatment plan for people with oral cancer who have a high risk of the cancer returning. After initial surgery and radiation/chemotherapy, a blood test will check for leftover cancer cells. If the test is positive, patients will receive l…

This study is testing a new AI system that uses video to measure how wide someone can open their jaw and how far they can move their shoulder. Researchers will compare the AI's measurements to those taken with standard tools like calipers. They aim to see if the AI is accurate, e…

This study is testing whether starting a structured tongue-strengthening exercise program early, using a special biofeedback device called a Tongueometer, can lead to better speech and swallowing recovery for people after tongue cancer surgery. It will involve 40 adults who are h…

This study aims to find the best pain relief combination for patients recovering from oral cancer surgery. Researchers will compare two different painkiller mixes given through patient-controlled pumps after surgery. They want to see which provides better pain control with fewer …

This study checks if the benefits of a special AI-guided physical therapy program last over time for people recovering from oral cancer. It follows 65 patients for 9 months after their therapy ends to see if they keep better jaw and shoulder movement, less pain, and a better qual…

This study is testing whether AI-guided physical therapy can help oral cancer patients maintain better movement and quality of life during treatment. One hundred newly diagnosed patients will either use a smartphone app that guides their jaw, neck, and shoulder exercises or recei…

This study tests whether an AI-powered chatbot or traditional educational handouts are more effective at teaching people about oral cancer prevention. Researchers will work with 60 African American adults from the Richmond area, randomly assigning them to learn from either the ch…

This study aims to understand why some oral cancers are more aggressive and how patients respond to treatments. Researchers will collect tissue samples from 1,000 adults with oral cancer or pre-cancerous conditions before, during, and after their standard treatments. The goal is …

This study aims to understand the source of pain in oral cancer by comparing how patients and healthy people feel pressure and stretching on the tongue. Researchers will measure pain sensitivity in 40 oral cancer patients and 40 healthy volunteers. The goal is to gather knowledge…

This study aims to understand if changes in the natural bacteria in our mouth and gut (the microbiome) play a role in causing head and neck cancers. Researchers will collect saliva and stool samples from 60 people, including those with and without oral cancer, to analyze the bact…