ORAL CANCER

This study tests whether giving a short course of focused radiation (SBRT) along with chemotherapy and immunotherapy before surgery can help people with advanced mouth or throat cancer live longer without the cancer coming back. About 184 adults aged 18 to 75 with untreated, adva…

This study tests whether mixed reality (MR) technology can help surgeons remove oral cancer and rebuild the area more precisely. Thirty people with oral cancer will be split into three groups: one using MR goggles, one using a virtual surgical guide, and one having standard surge…

This study tests a new, low-cost handheld device that uses light therapy (photodynamic therapy) to treat pre-cancerous and early cancerous mouth lesions. The goal is to see if this treatment can destroy these lesions without needing surgery. The study will enroll 65 adults with h…

This study tests whether a mobile app with swallowing exercises can help people recovering from oral cancer surgery. About 72 adults in Taiwan will either get standard care or use the app for 12 weeks. Researchers will check if the app improves swallowing, reduces anxiety, and bo…

This study looks at whether rinsing with hydrogen water can help reduce pain, swelling, and mouth sores in people recovering from oral cancer surgery that involved rebuilding part of the mouth with a skin flap. About 36 adults will be randomly assigned to receive either hydrogen …

This study looks at 10 oral cancer patients who had neck surgery and now have shoulder blade movement problems. Researchers will use ultrasound to measure changes in a key shoulder muscle and see how it relates to arm movement. The goal is to see if ultrasound can be a useful too…

This early-phase study compares an inhaled version of the cancer drug afatinib to the standard oral pill in 24 healthy adult smokers. Researchers want to see if the inhaled form delivers the drug more directly to the lungs with fewer side effects. Participants will receive both f…