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Sound waves in the OR: could ultrasound help surgeons cut out oral cancer better?

NCT ID NCT07203911

Disease control Sponsor: Tobias Todsen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using ultrasound during oral cancer surgery helps surgeons remove tumors more completely. About 150 adults with early-stage oral cancer will be randomly assigned to standard surgery or surgery guided by real-time ultrasound. The goal is to see if ultrasound leads to clearer margins, fewer repeat surgeries, less need for radiation, and better quality of life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Aug 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria • Patients scheduled for surgical treatment of biopsy-proven T1-T3 oral squamous cell carcinoma. Exclusion criteria * Age \< 18 years. * Oral cancer with suspected bone involvement. * Unable to understand verbal or written information. * Prior radiotherapy treatment of oral cavity cancer. * Tumor not visible on ultrasound.

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Conditions

The condition(s) this trial relates to.

lip and oral cavity carcinoma Mouth Neoplasms oral cavity squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck tongue cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Oral cancer Squamous cell carcinoma of the oral cavity or oropharynx Tongue cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    7 sites in 5 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Otorhinolaryngology Head and Neck Surgery

    RECRUITING

    Aarhus, 8200, Denmark

  • Department of Otorhinolaryngology Head and Neck Surgery and Audiology, Rigshospitalet

    RECRUITING

    Copenhagen, Denmark

  • Emory University Hospital

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

  • Groote Schuur

    NOT_YET_RECRUITING

    Cape Town, 7935, South Africa

  • Istituto Nazionale Tumori of Milan

    NOT_YET_RECRUITING

    Milan, 20133, Italy

  • Karolinska Institute

    RECRUITING

    Stockholm, 17177, Sweden

  • Stanford Otolaryngology - Head & Neck Surgery Department

    NOT_YET_RECRUITING

    Stanford, California, 94305, United States

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