OPIOID USE DISORDER
Clinical trials for OPIOID USE DISORDER explained in plain language.
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App aims to boost opioid treatment start after ER visits
Disease control TerminatedThis study tested a smartphone app designed to help people with opioid use disorder begin and continue medication-assisted treatment after leaving the emergency room or hospital. The app used rewards to encourage patients to schedule and attend their outpatient Suboxone appointme…
Matched conditions: OPIOID USE DISORDER
Phase: NA • Sponsor: Q2i, LLC • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New approach to starting opioid addiction treatment avoids withdrawal
Disease control TerminatedThis study tested a new method for starting buprenorphine (a medication for opioid use disorder) that avoids the usual withdrawal symptoms. Instead of stopping all opioids first, patients started with very low doses of buprenorphine while still taking their regular opioids. The s…
Matched conditions: OPIOID USE DISORDER
Phase: PHASE4 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated May 18, 2026 11:59 UTC
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Restless legs drug may ease opioid withdrawal symptoms
Symptom relief TerminatedThis study tested whether pramipexole, a drug for restless legs syndrome, could reduce symptoms of both restless legs and opioid withdrawal in people recovering from opioid use disorder. The goal was to help them feel better and stay in treatment. The study was planned for 75 adu…
Matched conditions: OPIOID USE DISORDER
Phase: PHASE2, PHASE3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:10 UTC
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New hope for pain patients trapped by opioid addiction?
Symptom relief TerminatedThis study looked at whether buprenorphine can safely control chronic pain in people who are dependent on opioid painkillers, while also preventing withdrawal symptoms. Only 4 people were enrolled before the study was stopped early. The goal was to see if buprenorphine could impr…
Matched conditions: OPIOID USE DISORDER
Phase: PHASE4 • Sponsor: Theresa Jacob, PhD, MPH • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Can a simple device replace drugs for opioid withdrawal?
Symptom relief TerminatedThis study tested a device called Bridge to see if it could reduce opioid withdrawal symptoms. Researchers compared the real device to a fake one in 13 adults with opioid use disorder. The goal was to find a non-drug way to help people feel better during withdrawal.
Matched conditions: OPIOID USE DISORDER
Phase: NA • Sponsor: Masimo Corporation • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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HIV and opioid treatment study halted early – what researchers hoped to learn
Knowledge-focused TerminatedThis study looked at how different medications for opioid use disorder (methadone, buprenorphine, or naltrexone) affect immune system recovery in people with HIV who also inject opioids. Researchers measured markers of immune activation and gut health over 24 weeks. The study was…
Matched conditions: OPIOID USE DISORDER
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 26, 2026 03:23 UTC
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Opioid study cut short: only 2 volunteers tested
Knowledge-focused TerminatedThis study aimed to understand how withdrawal symptoms and drug-related cues affect decision-making in people with opioid use disorder. Researchers used choice tasks to see if participants would pick options with higher rewards. The study was terminated early and only enrolled 2 …
Matched conditions: OPIOID USE DISORDER
Phase: EARLY_PHASE1 • Sponsor: Joshua A. Lile, Ph.D. • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC