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Restless legs drug may ease opioid withdrawal symptoms

NCT ID NCT04759703

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 29 times

Summary

This study tested whether pramipexole, a drug for restless legs syndrome, could reduce symptoms of both restless legs and opioid withdrawal in people recovering from opioid use disorder. The goal was to help them feel better and stay in treatment. The study was planned for 75 adults but was terminated early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Gavin Foundation Clinical Stabilization Services

    Quincy, Massachusetts, 02170, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.