MENOPAUSE

This study tests whether estrogen patches can improve healing and reduce pain after rotator cuff surgery in post-menopausal women. About 58 women aged 50-80 will receive either an estradiol patch or a placebo patch for a short time after their operation. The goal is to see if the…

This study tests whether a daily prebiotic drink can improve blood sugar control in 30 postmenopausal women aged 45-60 who have prediabetes. Participants will drink a prebiotic beverage for 4 weeks, and researchers will measure changes in fasting glucose and other metabolic marke…

This study tests whether daily lutein from microalgae can slow age-related mental decline and reduce inflammation in 300 postmenopausal women with belly obesity. Participants will take either 6 mg, 14 mg of lutein, or a placebo for 6 months. Researchers will measure changes in me…

This study will follow 2,725 women aged 45-75 to see if newer forms of hormone replacement therapy (like creams, gels, and sprays) affect their risk of heart disease. The researchers want to find out if these modern treatments are safer for the heart than older methods. Participa…

This study tests whether taking blackcurrant supplements can help prevent bone loss in women after menopause. The researchers think blackcurrants may work by improving the balance of bacteria in the gut. The study will involve 159 women aged 45-70 who are not on hormone therapy, …

This study follows 2,100 women under 55 who had a hysterectomy to see if also removing the fallopian tubes brings on menopause earlier. Participants will provide small blood samples and answer online questionnaires twice, one year apart. The goal is to understand the menopausal i…

This study adapts a type of talk therapy (CBT-Meno) specifically for women veterans aged 45 and older who are going through menopause and have a major mental illness. The goal is to see if this tailored therapy is acceptable and helpful for improving their daily functioning and q…

This study tests whether four weekly motivational interviewing sessions can reduce false beliefs about menopause and help women grow from the experience. About 96 postmenopausal women will be randomly assigned to either the talking therapy or usual care. The goal is to see if thi…

This study tests whether an 8-week mindfulness program can reduce hot flashes and improve sleep in menopausal women. 90 women aged 45-60 with hot flashes and poor sleep will either join the program or receive no treatment. The program includes breathing exercises, body scans, and…

This study looks at whether a 12-week online facial yoga program can help menopausal women feel less stressed, think more clearly, and lower a stress hormone called cortisol. One hundred women aged 45-65 will be split into two groups: one does facial yoga twice a week, and the ot…

This study looks at whether a 12-week program of foot and ankle exercises can improve strength, balance, and quality of life in menopausal women aged 45 to 65. About 70 women will either do the exercises or continue their usual activities. The goal is to see if targeting the feet…

This study tests a testosterone gel applied to the skin to see if it can safely improve sexual interest and desire in women going through menopause. About 150 women aged 40-65 with low libido will receive either the gel or a placebo for several months. The goal is to provide a ne…

This study compares two vaginal treatments—estrogen and DHEA—for relieving menopause symptoms like vaginal dryness, pain during sex, and urinary issues. About 324 women aged 40-90 will be randomly assigned to one treatment and complete questionnaires and tests. The goal is to hel…

This study looks at whether clinical hypnosis and self-hypnosis can improve quality of life and reduce hot flashes in menopausal women who cannot or choose not to take hormone therapy. About 94 women will be randomly assigned to either hypnosis sessions or a supportive listening …

This study looks at whether laughter yoga can help menopausal women feel better. It will involve 80 women who are in menopause. Half will do 8 sessions of laughter yoga, and the other half will not. Researchers will check if laughter yoga improves menopause symptoms, sleep, and q…

This study explores whether a gentle, noninvasive electrical brain stimulation technique called transcranial electrical stimulation (TES) can help relieve common menopause symptoms like hot flashes, depression, anxiety, memory problems, and muscle discomfort. Researchers will tes…

This study tests whether hormone therapy (estrogen with or without progesterone) can safely reduce hot flashes and night sweats in women with HIV. Researchers will also check if it improves sleep, mood, thinking, bone health, and heart health. The trial will enroll 105 women aged…

This study aims to learn more about the menopause transition by collecting data from wearable devices and a smartphone app. Researchers will track symptoms and daily experiences in 1,250 women aged 35-55. The goal is to help women and doctors better understand and manage this lif…

This study aims to understand how women aged 45 to 60 experience and think about menopause, especially when they take part in a group-based program at a hospital in Paris. Researchers want to learn about the physical, emotional, and social aspects of menopause that often go unspo…

This study looks at how to help VA medical centers better serve women Veterans, especially those in midlife. Researchers will test two different strategies to get more women involved in programs for heart health, weight management, and stress. The study involves 18 VA sites and f…

This study looks at how menopause changes the way the body processes escitalopram, a common antidepressant. Researchers will compare drug levels in premenopausal and postmenopausal women aged 40-60 who take the medication for depression or anxiety. The goal is to help doctors per…

This study looks at how menopausal hormone therapy (MHT) affects the heart's ability to pump blood in women aged 45 to 60. Researchers will compare heart function between women using MHT and those who are not. The goal is to better understand the relationship between menopause, h…

This study looks at how menopause and poor sleep change heart structure and function in women aged 48-58 with type 2 diabetes. Researchers will use heart ultrasounds to measure early signs of heart strain. No treatment is given; the goal is to better understand these risks.