Algae extract could shield menopausal brains from mental decline
NCT ID NCT07600567
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a daily lutein supplement made from microalgae can slow cognitive decline in postmenopausal women with obesity. 300 women aged 48-60 will take either 6 mg, 14 mg, or a placebo for 180 days. Researchers will measure changes in memory, attention, and inflammation markers.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Lutein (from microalgae)
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help protect thinking skills and reduce inflammation in postmenopausal women.
- What could go wrong
- This is an early-stage trial with no phase designation, so results are uncertain. The study only includes a specific group (postmenopausal women with obesity), so findings may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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48 to 60 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Females * Age 48-60 years * Postmenopausal status (natural menopause, up to 5 years after menopause) * waist circumference ≥ 88 cm Exclusion Criteria: * Diagnosis of dementia or cognitive impairment * Use of hormone replacement therapy within the last 6 months * Advanced age-related macular degeneration * History of major untreated neurological or psychiatric disorders (including depression, Parkinson's disease, Alzheimer's disease, psychiatric disorders, stroke within the last 3 months) * Presence of chronic diseases, including: diabetes mellitus (type 1 or 2), lipid disorders, cardiovascular diseases, thyroid diseases, anemia, liver diseases, gastrointestinal disorders, or cancer within the last 5 years * Use of anti-inflammatory medications or medications targeting lipid or carbohydrate metabolism within the last 3 months * Alcohol consumption \> 100 g per week * Use of lutein-containing supplements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Food Science and Nutrition, Poznan University of Life Sciences
Poznan, 60-637, Poland
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