MAJOR DEPRESSION
Clinical trials for MAJOR DEPRESSION explained in plain language.
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Diabetes program for mental health patients pulled before start
Disease control TerminatedThis study aimed to see if a lifestyle program called Lifestyle MIND could help people with serious mental illness manage or prevent type 2 diabetes. Participants would have been randomly assigned to join the program right away or later. The study was withdrawn before any partici…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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New brain zapping technique targets tough depression
Symptom relief OngoingThis study tests a new type of brain stimulation for people with depression that hasn't improved with standard treatments. Ten adults will receive both active and sham (fake) stimulation in random order to see if the real treatment reduces symptoms. The goal is to find a safe and…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: Ruijin Hospital • Aim: Symptom relief
Last updated May 26, 2026 02:44 UTC
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One-Size-Fits-All therapy put to the test – but study never started
Knowledge-focused TerminatedThis study aimed to see if a general form of group therapy, using skills common to all major therapies, could help adults with depression, anxiety, PTSD, or stress. It was designed for people 18 and older with self-reported distress, but excluded those with recent self-harm, suic…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated May 26, 2026 02:57 UTC
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Depression food test study pulled before it began
Knowledge-focused TerminatedThis study was designed to test a new computer-based tool that uses pictures of food to measure pleasure and motivation in people with major depression. The goal was to compare responses between depressed patients and healthy volunteers to better understand reward processing. How…
Matched conditions: MAJOR DEPRESSION
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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ECT anesthesia study: does ketamine boost mood better than propofol?
Knowledge-focused OngoingThis study observes 65 adults with major depression or bipolar depression who are receiving electroconvulsive therapy (ECT) as part of their routine care. Researchers track how two different anesthetics—ketamine plus propofol versus propofol alone—affect depression severity, suic…
Matched conditions: MAJOR DEPRESSION
Sponsor: Nurdan Sağbaş • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC