MAJOR DEPRESSION
Clinical trials for MAJOR DEPRESSION explained in plain language.
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Veterans with tough depression to try psychedelic therapy in major trial
Symptom relief Not yet recruitingThis study tests whether psilocybin, a psychedelic substance, can help U.S. military veterans with depression that hasn't improved with standard treatments. About 240 veterans will receive psilocybin in a controlled setting, and researchers will measure changes in depression symp…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE3 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 26, 2026 09:59 UTC
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Can a magic mushroom drug work while You're asleep? new study aims to find out
Symptom relief Not yet recruitingThis study tests whether giving psilocybin (the active ingredient in magic mushrooms) to people under general anesthesia can safely reduce symptoms of major depression. By using anesthesia, neither the participant nor the researchers will know who got the real drug, making the re…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE2 • Sponsor: Stanford University • Aim: Symptom relief
Last updated May 26, 2026 09:56 UTC
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Can a psychedelic inhaler lift depression in hours?
Symptom relief Not yet recruitingThis study tests whether inhaling DMT, a fast-acting psychedelic, can quickly reduce depression and suicidal thoughts. 140 adults with major depression will receive either a high or low dose, and those not better after a week can get an extra high dose. The goal is to see if DMT …
Matched conditions: MAJOR DEPRESSION
Phase: PHASE2 • Sponsor: Universidade Federal do Rio Grande do Norte • Aim: Symptom relief
Last updated May 19, 2026 12:00 UTC
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LSD shortcut: could a quick trip ease depression?
Symptom relief Not yet recruitingThis early-stage study tests whether a shortened LSD experience, combined with the drug risperidone, is safe and effective for people with severe major depression. Ten adults with moderate to severe depression will receive LSD followed by risperidone 45 minutes later. The goal is…
Matched conditions: MAJOR DEPRESSION
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 19, 2026 11:59 UTC