Withdrawn depression study sought to measure food cravings with a computer test
NCT ID NCT03060967
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study was designed to test a new computer-based tool that uses pictures of food to measure how much pleasure and motivation people with major depression feel. The goal was to compare these responses between depressed patients and healthy volunteers to better understand depression. However, the study was withdrawn before any participants were enrolled, so no results are available.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Started
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Sep 2017
- Finished
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Jul 2018
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Depressed patient group 1. to be between 20- and 60-year-old; 2. to meet the DSM-5 diagnostic criteria for major depressive disorder; 3. to experience moderate to severe symptoms interfering with the daily functioning, as indicated by a score above 20 on the Montgomery and Asberg depression scale (MADRS); 4. to understand and accept the experimental procedure and constraints of the present study; 5. to give written consent for the participation to the study; and, 6. to be a beneficiary of or affiliated to a health insurance plan. Healthy volunteer group 1. to be between 20- and 60-year-old; 2. to be free from any history of psychiatric disorder (substance abuse or alcohol abuse, dependence, mood disorders, etc.) that may require the prescription of long-term psychotropic treatment; 3. to understand and accept the experimental procedure and constraints of the study; 3\) to give written consent for the participation to the study; and, 4) to be a beneficiary of or affiliated to a health insurance plan Exclusion Criteria: * Depressed patient group 1. to have a previous history of somatic disease (hypertensive heart disease, Raynaud's syndrome, diabetes, adrenal insufficiency, Cushing's syndrome, peripheral neuropathy, epilepsy ...) or requiring long-term corticosteroid therapy; 2. to experience serious visual disturbances affecting the visual perception of colors; 3. to meet the DSM-5 diagnostic criteria for a primary psychiatric disorder such as bipolar disorder, schizophrenia, substance abuse / dependence or alcohol abuse, except for social phobia and generalized anxiety disorder that are commonly comorbid to major depression; 4. to exhibit a moderate or high suicidal risk, assessed by using the corresponding section of the so-called structured diagnostic psychiatric interview "Mini International Neuropsychiatric Interview" (M.I.N.I. 6.0); 5. to be exposed to the initiation of an antidepressant treatment with either a selective serotonin reuptake inhibitor or a dual serotonin-norepinephrine reuptake inhibitor within the week prior to the study or to be exposed to a change in the daily dosage of such an ongoing antidepressant treatment within the week preceding the study due to its potential sedative and orexigenic properties; 6. to be exposed to an antidepressant treatment with antagonists at the presynaptic alpha-2 norepinephrine receptors or with tricyclic agents within the week prior to the study due to their potential sedative and orexigenic properties related to their anti-H1 pharmacological profile; 7. to be exposed to the initiation of anxiolytic/hypnotic treatment within the week before the study or to be exposed to a change in the daily dosage of such an ongoing anxiolytic/hypnotic treatment within the week prior to the study due to its potential sedative properties in relation with its GABAergic activity; 8. to be exposed to an antipsychotic treatment within the week prior to the study due to its potential sedative and orexigenic properties related to its anti-H1 pharmacological profile; 9. to be exposed to alcohol consumption within 2 days before the study 10. to have a body mass index \<18.5 or ≥ 30; 11. to undergo involuntary hospitalization; 12. to be a pregnant, parturient or nursing women; 13. to be a subject deprived of its liberty by judicial or administrative decision 14. to be a subject under the safeguard measures; and, 15. to be a subject undergoing an exclusion period for another clinical research Healthy volunteer group 1. to have a previous history of somatic disorders, including neurological disease; 2. to experience serious visual disturbances affecting the visual perception of colors; 3. to be exposed to alcohol consumption within 2 days before the study 4. to have a body mass index \<18.5 or ≥ 25; 5. to undergo involuntary hospitalization; 6. to be a pregnant, parturient or nursing women; 7. to be a subject deprived of its liberty by judicial or administrative decision 8. to be a subject under the safeguard measures; and, 9. to be a subject undergoing an exclusion period for another clinical research
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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NeuroCentre Magendie INSERM U862
Bordeaux, 33077 Bordeaux Cedex, France
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Other studies related to the condition(s) this trial covers.
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