LYNCH SYNDROME

This early-stage trial tests a custom-made vaccine for people with Lynch syndrome, a genetic condition that raises cancer risk. The vaccine uses the patient's own immune cells to target unique cancer markers. The goal is to see if it's safe and can train the body to fight off tum…

This study is testing a web-based program called Kindred to see if it helps African American families better understand their genetic cancer risk and get tested for hereditary cancer syndromes. About 150 people will use the online tool to learn about their test results and how to…

This study checks if a newer, cheaper DNA sequencing machine (MGI) works as well as the current standard (Illumina) for finding gene changes linked to hereditary cancers like breast, ovarian, and Lynch syndrome. Researchers will compare results from both machines using the same D…

This study looks at 150 people with Lynch syndrome to find out how many also have Muir-Torre syndrome, a condition that causes certain skin tumors. Researchers will check skin lesions and past tumor samples using lab tests. The goal is to better understand the connection between …

This study looks at whether easy-to-collect samples like blood, urine, stool, and vaginal swabs can help predict cancer in people with Lynch syndrome, a genetic condition that raises cancer risk. Currently, patients need invasive procedures like colonoscopies. The goal is to see …

This study tests an online tool called Let's Talk to help people with Lynch syndrome encourage their relatives to get screened for cancer risk. Researchers will work with 20 participants (15 patients and 5 genetic counselors) to see if the tool is easy to use and improves knowled…

This study looks at whether a tiny camera in a capsule, which you swallow, can be a good alternative to standard colonoscopy for people with Lynch syndrome. Lynch syndrome greatly raises the risk of colon cancer, so regular screening is important. The capsule camera is less invas…