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Personalized vaccine aims to stop lynch syndrome cancers before they start

NCT ID NCT07609901

First seen Jun 02, 2026 · Last updated Jun 15, 2026 · Updated 3 times

Summary

This phase III trial tests whether a vaccine made from a person's own immune cells can prevent cancer in 372 adults with Lynch syndrome, a genetic condition that raises cancer risk. Participants receive either the vaccine or a placebo and are monitored for tumor development. The goal is to see if the vaccine can keep cancer from forming.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Radboudumc

    Nijmegen, Gelderland, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Colorectal Neoplasms, Hereditary Nonpolyposis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.