Personalized vaccine aims to stop lynch syndrome cancers before they start

NCT ID NCT07609901

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase III trial tests whether a vaccine made from a person's own immune cells can prevent cancer in 372 adults with Lynch syndrome, a genetic condition that raises cancer risk. Participants receive either the vaccine or a placebo and are monitored for tumor development. The goal is to see if the vaccine can keep cancer from forming.

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Conditions

The condition(s) this trial relates to.

Colorectal Neoplasms, Hereditary Nonpolyposis Lynch syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Radboudumc

    Nijmegen, Gelderland, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.