Could a pill camera replace colonoscopy for lynch syndrome patients?
NCT ID NCT07445828
First seen Mar 13, 2026 · Last updated Jun 23, 2026 · Updated 15 times
Summary
This study tests whether a swallowable capsule with tiny cameras can effectively screen for colon cancer in people with Lynch syndrome, a genetic condition that greatly increases colon cancer risk. Participants will undergo both the capsule exam and a standard colonoscopy to compare how well each detects polyps and other abnormalities. The goal is to see if the capsule, which is less invasive and doesn't require sedation, could be a more comfortable alternative for regular surveillance.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Skane University Hospital Malmö
Malmö, Skåne County, 20502, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
colon capsule endoscopy
What this could lead to
If successful, this could offer a less invasive, more comfortable screening option for people with Lynch syndrome, potentially improving adherence to regular surveillance.
What could go wrong
This is a small, early-phase study (78 participants) comparing the capsule to standard colonoscopy. The capsule may miss some polyps, and bowel preparation is critical but cannot be adjusted during the procedure.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.