Could a pill camera replace the colonoscopy for lynch syndrome patients?

NCT ID NCT07445828

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a swallowable capsule camera (colon capsule endoscopy) can effectively screen for colorectal cancer in people with Lynch syndrome, a genetic condition that greatly increases cancer risk. Researchers will compare the capsule's ability to find polyps and other abnormalities against the standard colonoscopy in 78 participants. The goal is to see if this less invasive method is safe, accurate, and more comfortable for patients who need frequent surveillance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
colon capsule endoscopy (a swallowable camera device)
What this could lead to
If successful, this could offer a less invasive, more comfortable screening option for people with Lynch syndrome, potentially improving adherence to regular surveillance.
What could go wrong
This is a small, early-stage study (78 participants) comparing a new method to the standard. The capsule may miss some polyps, and bowel preparation is critical. Results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

Colorectal Neoplasms, Hereditary Nonpolyposis Lynch syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Skane University Hospital Malmö

    Malmö, Skåne County, 20502, Sweden

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