LIVER TRANSPLANTATION

This study compared two different methods for managing bleeding during liver transplant surgery. Researchers tested whether using a specialized blood test (called ROTEM) during surgery would reduce the need for blood transfusions compared to standard blood tests. The trial involv…

This study tested whether using a special machine to pump a cold, oxygenated solution through a donor liver before transplant could improve outcomes. It focused on livers from higher-risk donors, which are more likely to have early problems after surgery. Researchers compared thi…

This study looked at whether a two-step machine perfusion technique could safely prepare and test higher-risk donor livers for transplantation. Researchers used the machine to revive and assess 206 livers from donors that would typically be considered too risky, then transplanted…

This study tested if switching children with stable organ transplants from a twice-daily anti-rejection pill (Prograf) to a new once-daily version (Advagraf) was safe and kept the right amount of medicine in their blood. It involved 81 children who had received a heart, kidney, l…

This study looked at a new surgical method for patients with severe blood clots in a major liver vein who needed a transplant. Doctors used a small ligament from the donor liver to help restore blood flow during the operation. The goal was to make these complex transplants safer …

This study looked back at nearly 500 liver cancer patients who received a liver transplant. Researchers wanted to see if taking certain cancer-fighting drugs (tyrosine kinase inhibitors) before the transplant surgery helped control the cancer better. They checked if the drugs led…

This study tested whether giving low-dose IL-2 injections to liver transplant patients could boost special immune cells called Tregs. Researchers hoped increasing Tregs might help the body accept the transplanted liver better, potentially allowing patients to reduce their anti-re…

This study tested whether providing structured home exercise instructions could help people feel better after a liver transplant. Researchers compared giving exercise advice through a brochure, a video, or just standard care. They wanted to see if these simple tools could help pe…

This study tested whether a 12-week exercise program delivered via video calls could help adults recover after a liver transplant. 140 participants were randomly assigned to either receive standard care or the video exercise sessions twice a week. The goal was to see if this conv…

This study tested whether a special exercise program could help liver transplant patients. It compared standard physical therapy to exercises that combine movement with thinking tasks. The goal was to see if these 'motor-cognitive' exercises could improve memory, balance, and wal…

This study looked back at medical records to see if patients who were already taking cholesterol-lowering statin drugs before their liver transplant had fewer serious heart problems after surgery. Researchers reviewed the records of 6,871 adult liver transplant recipients to chec…

This study aimed to understand if patients with muscle loss (sarcopenia) need different amounts of a muscle relaxant drug during liver transplant surgery. Researchers observed three adult patients undergoing a transplant, measuring their muscle strength before surgery and trackin…

This study aimed to understand how caring for a loved one getting a liver transplant affects the caregiver's own health. Researchers followed 119 caregivers, measuring their fatigue, stress, and physical activity levels before the transplant and again at 3 and 6 months after. The…

This study aimed to create better mathematical models to predict which patients with severe liver cirrhosis are most likely to die while waiting for a transplant. Researchers analyzed data from 501 patients on the national waitlist, testing new combinations of health measurements…