LIVER TRANSPLANTATION

This study looked at whether giving liver transplant patients simple exercise instructions—via a brochure or a video—could help them become more active, feel less tired, and reduce the burden on their caregivers. Over 100 adults who had a liver transplant were split into three gr…

This study tested a new way to treat severe blood clots in the portal vein during liver transplant surgery. Doctors used a special approach through the ligament of the liver to place stents or close off abnormal veins. The study included 75 patients and compared results before an…

This study looked at whether combining physical and mental exercises can help people who had a liver transplant. 32 adults did either standard physical therapy or a program that mixed movement with thinking tasks. The goal was to see if these combined exercises improve memory, ba…

This study tested a 12-week exercise program done at home via video calls for 140 adults who had a liver transplant. The goal was to see if it could improve muscle strength, exercise ability, and fatigue. Participants were randomly assigned to either the remote exercise group or …

This study tested a method called HOPE, which gently pumps oxygenated cold fluid through donor livers before transplant. It included 266 adults receiving a liver from an older or higher-risk donor. The goal was to see if HOPE reduces early liver problems after surgery compared to…

This study tested whether very low doses of a protein called IL-2, given as under-the-skin injections for 4 weeks, could increase the number of helpful immune cells (Tregs) in liver transplant recipients. The goal was to see if this approach might improve the body's acceptance of…

This study looked at whether livers from older or less ideal donors could be safely used for transplant after being treated with a special machine that pumps fluids through them. Researchers followed 143 adult patients who received these revived livers. The goal was to see how we…

This study involved 81 children who had received an organ transplant (like kidney, liver, or heart) and were taking a standard anti-rejection drug called Prograf. Researchers wanted to see if switching to a longer-acting version called Advagraf was safe and worked just as well. T…

This study looked at 501 adults with severe liver disease waiting for a transplant. Researchers created new mathematical models to better predict which patients are at highest risk of dying while waiting. The goal is to make the transplant system fairer and save more lives.

This study looked back at data from 484 liver cancer patients who had a liver transplant. Researchers wanted to see if taking certain cancer drugs (tyrosine kinase inhibitors) before the transplant helped patients live longer or kept the cancer from coming back. The goal was to f…

This study tested whether a structured program combining exercise, nutrition advice, and psychological support is practical and safe for adults with cirrhosis waiting for a liver transplant. 25 participants were enrolled. The goal was to see if patients could stick with the progr…

This completed study looked at 3 liver transplant patients to see if muscle loss (sarcopenia) changes how the body reacts to the muscle relaxant rocuronium. Researchers measured hand grip strength and used a questionnaire to diagnose sarcopenia before surgery. The goal was to fin…

This study compared two methods of liver biopsy—one through a thin needle through the skin (percutaneous) and another using an endoscope through the mouth (EUS-guided)—to see which one patients liked better. 102 adults with chronic liver disease were randomly assigned to one of t…

This study looked at 82 adults getting a liver transplant to see if using a special blood test called ROTEM helps doctors manage bleeding better than standard tests. The goal was to see if ROTEM could reduce the amount of blood products given during surgery. Researchers tracked c…

This study looked at 119 caregivers of liver transplant patients to see how their fatigue, burden, and physical activity changed before and after the transplant. Caregivers were assessed at three points: before the transplant, 90 days after, and 180 days after. The goal was to un…

This study reviewed the records of nearly 7,000 adults who had a liver transplant to see if taking statins beforehand lowered their risk of serious heart problems, like heart attack or stroke. Researchers compared those who used statins before surgery to those who did not. The go…