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Could a common cholesterol pill shield heart during liver transplant?

NCT ID NCT07089589

Knowledge-focused Sponsor: Asan Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked back at the records of nearly 7,000 adults who had a liver transplant to see if taking statins beforehand lowered their risk of major heart problems. Researchers checked for events like heart attack, stroke, and heart failure within 30 days after surgery. The goal is to find out if this simple, existing medication could offer extra protection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
statin drugs (e.g., atorvastatin, simvastatin)
What this could lead to
If statins are found to be helpful, this could lead to a simple, low-cost way to lower heart risks before liver transplant.
What could go wrong
This is an observational study, not a controlled trial, so it can only show links, not cause and effect. The results may be influenced by other health factors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

6,898 people

The number who actually took part.

Started

Jan 2008

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (≥18 years) who underwent liver transplantation at Asan Medical Center, Samsung Medical Center, and Inje University Haeundae Paik Hospital in Korea between January 2008 and January 2026.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Adult patients aged ≥18 years who underwent liver transplantation Exclusion Criteria: * Patients who underwent liver re-transplantation * Patients with preoperative acute-on-chronic liver failure (ACLF) * Patients with preoperative fulminant hepatic failure

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Liver transplantation Major adverse cardiovascular events

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

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