LIVER CANCER

This early study tested a new drug called Cabotamig (ARB202) in 33 adults with advanced gastrointestinal cancers (like stomach, liver, or bowel cancer) that had stopped responding to standard treatments. The drug works by targeting a marker called CDH17 on cancer cells and helpin…

This study looked at whether a precise type of radiation called proton beam therapy can control liver cancer that cannot be surgically removed. It included 83 adults with liver cancer. The goal was to see if this treatment can kill cancer cells while causing fewer side effects th…

This study tested a new combination treatment for people with liver cancer that cannot be removed by surgery. The treatment included chemotherapy delivered directly to the liver, a procedure to block the tumor's blood supply, and two drugs (lenvatinib and tislelizumab). The goal …

This early-stage study tested a new drug (BI 765049) alone or with another drug (ezabenlimab) in 21 Asian adults with advanced cancers like stomach, lung, or liver cancer that had stopped responding to treatment. The goal was to find a safe dose and see if the drugs could shrink …

This early-phase study tested a personalized vaccine made from yeast that is designed to teach the immune system to recognize and attack leftover cancer cells. It included 5 adults with different cancers who had already completed treatment aimed at curing their disease. The goal …

This study tested two chemotherapy drugs, cisplatin and mitomycin-C, given directly into the liver artery for people with liver cancer that cannot be surgically removed. The goal was to see how long it takes for tumors to grow and to monitor side effects. The study also looked at…

This study tested whether a special type of ultrasound with contrast dye (CEUS) can more accurately identify liver lesions found on regular ultrasound. Researchers compared CEUS to CT, MRI, and biopsy in 878 adults with liver spots. The goal was to see if CEUS could provide a rel…

This study tested whether a shorter, contrast-enhanced MRI (called AMRI) works better than standard ultrasound for finding liver cancer early in people with liver cirrhosis. Researchers enrolled 79 adults with cirrhosis and compared the accuracy of both imaging methods. The goal …

This study looked for new substances in the blood that could help diagnose liver cancer more accurately. Researchers tested blood samples from 573 people, including those with liver cancer, other liver diseases, and hepatitis infections. The goal is to improve upon current tests …

This study tested whether giving lidocaine through a vein during liver surgery can reduce pain and the need for strong painkillers afterward. 124 adults having minor liver surgery were randomly assigned to receive either lidocaine or a placebo (salt water). The main goal was to s…

This study is a registry that collected information from 332 liver cancer patients in France who were treated with SIR-Spheres, a type of internal radiation therapy. The goal was to describe how the treatment is used in real life and to report safety and effectiveness data to hea…

This study analyzed data from over 19,000 liver cancer patients to see if the risk of cancer spreading (metastasis) differs between men and women. Researchers used machine learning to create separate prediction models for each sex. The goal was to improve early detection and pers…

This study looked at 379 people with liver cancer to see if monitoring changes in blood markers over time, along with standard clinical information, could better predict how the disease will progress. The goal was to create a more accurate tool for doctors to personalize treatmen…

This study looked at 52 adults who had a living-donor liver transplant to see if using a microscope or surgical loupes (magnifying glasses) leads to fewer bile duct problems after surgery. The goal was to find out which tool helps reduce complications like leaks or narrowing of t…

This study tested whether a breath analysis test could help diagnose or predict the course of liver diseases, liver cancer, and COVID-19. Researchers collected breath samples from 46 participants to detect unique chemical patterns. The goal was to develop a non-invasive diagnosti…

This study created a worldwide registry for people with fibrolamellar cancer (FLC), a rare liver cancer. Researchers collected information from 12 participants about their medical history and routine care. The goal was to build a database that can be used for future studies. No t…

This study tested a new type of CT scanner that takes pictures during radiation therapy for lung, liver, breast, and other cancers. The goal was to see if the new scanner produces clearer images with fewer distortions. 31 people participated, and the results will help doctors bet…