A single blood draw to detect five cancers before symptoms appear?
NCT ID NCT06790355
First seen Sep 04, 2026 · Last updated Sep 04, 2026
Summary
This trial tests a blood-based test designed to detect multiple cancers early in people aged 40 to 74 who have no cancer symptoms. The study will enroll about 2,500 participants and will check how well the test identifies lung, colorectal, liver, gastric, and esophageal cancers. Researchers will also measure how often a positive test leads to a confirmed diagnosis and how quickly people get a clear answer after a positive result.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Blood-based multi-cancer early detection test
- What this could lead to
- If the test works, it could lead to a simple blood draw that helps catch several cancers early, when treatment is more likely to succeed.
- What could go wrong
- This is an early feasibility study, so the test may not be accurate enough or may cause unnecessary follow-up procedures. The results will need confirmation in larger trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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2,527 people
The number who actually took part.
- Started
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Mar 2025
- Finished
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Aug 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 74 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 40-74 years old * Able to provide a written informed consent and willing to comply with all parts of the protocol procedures Exclusion Criteria: * With cancer-associated clinical symptoms or suspected of cancer within 30 days prior to screen * Have definite contraindications of cancer screening examination and diagnostic procedures * Unable to comply with the protocol procedures * Personal history of cancer, diagnosed within the 3 years prior to expected enrollment date * Have received or are undergoing curative cancer treatment within three years prior to recruitment. Adjuvant endocrinotherapy for cancer is not an exclusion criterion. * Recipients of anti-tumor therapy within 30 days prior to screen * Pregnancy or lactating women * Recipients of organ transplant or prior bone marrow transplant or stem cell transplant * Recipients of blood transfusion within 7 days prior to screen * With autoimmune diseases * Have an acute infection or inflammation or uncontrolled chronic infection within 14 days prior to blood draw * Unsuitable for this trial determined by the researchers (eg. hemorrhagic diseases)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, 200032, China
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Fujian Cancer Hospital
Fuzhou, Fujian, 350014, China
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Henan Cancer Hospital
Zhengzhou, Henan, 450008, China
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Jiangsu Cancer Hospital
Nanjing, Jiangsu, 210009, China
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