HIP OSTEOARTHRITIS

This study is checking how well the Z1 Femoral Hip System works and how safe it is for people needing hip replacement. About 150 adults with hip problems like arthritis or fractures will be followed for 2 years. The main goal is to see how many implants are still in place without…

This study is tracking 49 people who already decided to get a total hip replacement using a special cup called the DELTA Revision cup. Researchers want to see how safe the cup is, how well patients can move, and how long the implant lasts over two years. The goal is to improve hi…

This study tests whether platelet-rich plasma (PRP) with or without white blood cells works better for hip osteoarthritis. 230 adults with mild to moderate hip arthritis will receive ultrasound-guided injections and be followed for a year. The goal is to see which type reduces pa…

This study tests two types of nerve blocks to see which one controls pain better after hip replacement surgery. About 90 adults aged 65 and older will receive either a PENG block or a combination of ESPB blocks before surgery. The goal is to reduce the need for strong painkillers…

This study compares three types of nerve blocks to see which provides the best pain relief after hip replacement while preserving leg strength for early walking. About 93 adults aged 65 and older will receive one of the blocks during surgery. The goal is to find the safest and mo…

This study looks at whether adding progressive resistance training to a patient education program helps people with hip osteoarthritis move better and feel less pain. 150 adults with hip OA will be randomly assigned to either education plus exercise or education alone. Researcher…

This study looks at whether adding a PENG nerve block to standard spinal anesthesia can lower the chance of postoperative delirium (sudden confusion) in adults aged 75 and older having hip replacement surgery. About 180 participants will be randomly assigned to receive either spi…

This study tests whether injecting steroids into muscle trigger points can reduce pain from chronic musculoskeletal pain, migraines, and hip osteoarthritis. About 1,036 adults aged 45 and older with persistent pain will receive either trigger point or joint injections and be foll…

This study looks at whether adding a small dose of dexmedetomidine to a standard nerve block can provide longer-lasting pain relief after hip surgery in adults 65 and older. Participants will be randomly assigned to receive either the standard block or the block with the added me…

This study compares three types of a nerve block (PENG block) for pain after hip surgery in people aged 65 and older. All participants get the standard block, but some also receive either dexamethasone or dexmedetomidine near the nerves to see if these additives extend pain relie…

This study tests whether a pre-surgery exercise program (prehabilitation) helps people waiting for hip or knee replacement. Researchers will measure quality of life, mobility, and mental health in 44 adults with osteoarthritis. The goal is to see if this simple, drug-free approac…

This study compares three versions of a nerve block (PENG block) in 120 adults aged 65 and older having hip surgery. All patients get the same base painkiller, but some also receive extra medications near the nerves or through a vein. The goal is to find which combination provide…

This study follows 432 golfers who have hip, knee, or shoulder replacement surgery. Researchers check in at 6 weeks, 3 months, 6 months, and 12 months after surgery to see if and how they return to golf. The goal is to learn more about the recovery process and what helps golfers …

This study compares two types of anesthesia—general (you are fully asleep) and spinal (you are awake but numb from the waist down)—for people having hip or knee replacement surgery. Researchers will track recovery time, pain, nausea, infections, and other complications in about 2…

This study looks at how well a particular type of knee replacement (a fixed polyethylene posteriorly stabilized cemented total knee prosthesis) works over time. Researchers will review medical records and X-rays from 960 adults who had this surgery between 2013 and 2024. The goal…

This study is testing a smartphone app that tracks movement and symptoms in people before and after knee or hip replacement surgery. The goal is to create a score that helps predict which patients will be satisfied with their surgery. About 1,250 adults in Germany will participat…

This study looks at hip and knee tissue from 1000 people having joint replacement surgery for osteoarthritis. Researchers want to measure levels of rare metals and immune markers in the joint tissue and blood. The goal is to find clues that could lead to better treatments, like m…

This study tracks 30 people getting a new hip replacement to measure how much the implant shifts over two years. Researchers use special X-ray techniques to check stability. The goal is to see if the implant stays in place as well as older models. Participants must need a hip rep…

This study compares two antiseptic washes (povidone-iodine vs. chlorhexidine) used during hip replacement surgery to see which leads to better wound healing. About 420 adults with hip osteoarthritis or avascular necrosis will be randomly assigned to one wash. Researchers will eva…