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Joint tissue study could unlock new osteoarthritis treatments

NCT ID NCT07347821

Knowledge-focused Sponsor: Medical University of Warsaw Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study looks at hip and knee tissue from 1000 adults with osteoarthritis who are scheduled for joint replacement surgery. Researchers want to measure levels of rare metals and immune markers in the joint tissue and blood. The goal is to find imbalances that could lead to better treatments, like metal supplements or immune therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients undergoing primary THA or TKA at the trauma and orthopedics department of the hospital in Ostrów Mazowiecka, as well as at the trauma and orthopedics department in Międzylesie Specialist Hospital in Poland.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years old and more * patient qualified for primary TKA or primary THA * patient diagnosed with hip or knee osteoarthritis * a complete set of tissues of good quality and volume is available * does not meet the exclusion criteria. Exclusion Criteria: * lack of written consent to participate in the study or surgery * any private or professional relationship with the Investigators * genetic connective tissue diseases (e.g., Ehlers-Danlos syndrome and others) * genetic metabolic diseases (e.g., gout and others) * genetic diseases affecting the anatomy of the operated joint (e.g., dysplasia and others) * previous surgeries altering the anatomy of the examined joint (e.g., periacetabular osteotomy, unicompartmental endoprosthesis, and others) * patients undergoing revision after THA/TKA * autoimmune diseases in the patient's medical history * traumatic injury to the hip or knee joint * previous participation in the study.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, hip osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hip osteoarthritis Knee osteoarthristis Total hip arthroplasty (THA) Total knee arthroplasty (TKA)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Szpital Powiatowy im. M. Skłodowskiej-Curie

    RECRUITING

    Ostrów Mazowiecka, Masovian Voivodeship, 07-300, Poland

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