HEALTHY PARTICIPANTS

This early-stage study tests an inhaled powder called SYH2059 in 84 healthy adults to see if it is safe and how the body processes it. Participants receive either the drug or a placebo, and researchers monitor side effects and drug levels in the blood. The goal is to gather safet…

This study aims to establish normal reference ranges for liver and other organs in healthy adults from different ethnic groups in Singapore. Fifty self-reported healthy participants will undergo an MRI to measure organ fat, size, and inflammation. The goal is to improve how docto…

This early-stage study tests a single dose of STLX-2012 in 32 healthy adults to check its safety and how the body processes it. Participants receive either the drug or a placebo by IV. No treatment benefit is expected; the goal is to gather safety data before testing in patients.

This study looks at how different parts of the brain's prefrontal cortex respond to magnetic stimulation in 34 healthy adults. Researchers will use high-field MRI and EEG to map brain connections and excitability. The goal is to find better targets for a therapy called rTMS, whic…

This study explores whether a safe, non-invasive electrical stimulation technique called temporal interference stimulation can temporarily alter brain activity during sleep. Researchers will focus on sleep spindles, which are brain rhythms linked to memory and learning. Up to 24 …

This early-phase trial will test the safety and how the body processes a new drug called NBX-100 in 8 healthy adults aged 21-50. Participants receive four weekly doses and have frequent check-ups and psychological support. The study does not aim to treat any disease, but to gathe…

This study looks at how different breathing patterns during strength exercises affect eye pressure and the tiny blood vessels in the retina. Researchers will measure these changes in 60 healthy adults aged 18-40 during both isokinetic and isometric exercises. The goal is to find …

This study looks at how plant sterols (natural compounds found in plants) affect a newly discovered gene called GPR146, which helps control cholesterol. Researchers will give 23 healthy adults three different test meals and measure gene activity in their blood and gut cells. The …

This study looks at whether exercising at different times of day changes how we feel pain afterward. Healthy adults aged 18-40 will do morning and evening sessions to see if pain sensitivity shifts. The goal is to understand how our body clocks influence pain relief from exercise…

This study aims to help 16,000 college students in Zimbabwe take better care of their sexual health using a mobile phone tool. The tool includes decision aids to guide choices about HIV prevention and contraception. Researchers will test if this approach increases the use of HIV …

This study looks at how different amounts of manual pressure on the upper back affect heart rate, stress hormones, and pain sensitivity in 90 healthy adults aged 18-65. Participants will be randomly assigned to receive either sustained pressure, kneading, or three different massa…

This study compares three fiber supplements—LOAM prebiotic fiber, inulin, and a placebo—to see which causes the least gas and digestive discomfort in healthy adults who eat a low-fiber diet. Participants take one daily serving for four weeks and wear a small device that tracks ga…

This study works with African Methodist Episcopal (AME) churches in South Carolina to see if they can successfully run a walking and healthy eating program called Walk Your Heart to Health. About 300 adults aged 50 and older will take part. Researchers will track how many steps p…

This study looks at how a special nutritional drink affects blood sugar levels in healthy adults. Researchers will compare the drink to pure glucose to measure its glycemic index. Thirty healthy volunteers will take part, each trying both products on different days. The goal is t…

This study tests whether a mild, painless electrical stimulation on the ear (called taVNS) can improve thinking skills like memory and attention in healthy adults aged 18-30. Each participant will receive both the real stimulation and a fake (sham) version in separate sessions to…

This study looks at whether a special warm-up that includes balance and coordination exercises works better than a standard warm-up for improving balance and strength in people who go to the gym regularly. About 46 healthy adults aged 18 to 40 will take part in 6 weeks of warm-up…

This observational study tracks 100 adults to see how Roux-en-Y gastric bypass surgery alters gut bacteria and related chemicals over 12 months. Researchers will compare people having surgery with those on diet alone and healthy individuals. The goal is to link specific gut chang…

This early-stage study tests the safety of a new drug, IBI3033, in 32 healthy Chinese adults aged 18-55. Participants receive a single dose of the drug or a placebo and are monitored for side effects and how the drug moves through the body over 12 weeks. The goal is to gather saf…

This early-stage study tests whether IBI3033 is safe and how it behaves in the body. Eight healthy adults will receive either the drug or a placebo. The goal is to check for side effects and measure drug levels, not to treat any disease.

This early-stage study tests a new drug called QL2302 in 178 healthy adults aged 18 to 45. It compares how the body processes QL2302 versus the approved drug Tezspire, and checks for side effects and immune responses after a single dose. The goal is to see if QL2302 works similar…

This early-stage study will compare two versions of evolocumab, a drug used to lower cholesterol, in 400 healthy adults aged 18 to 60. Participants will receive a single dose of one version, and researchers will measure how the drug moves through the body and check for side effec…

This study gives 50 healthy adults a single dose of psilocybin (the active ingredient in magic mushrooms) or a placebo to measure changes in brain waves, blood chemicals, and empathy. Participants must have never used psychedelics before. The goal is to understand how psilocybin …

This early-stage study tests a new drug, AK0406, in 32 healthy adults to see if it is safe and how the body processes it. Participants receive a single dose of the drug or a placebo, and researchers monitor for side effects. This is a first-in-human trial, so the main goal is saf…

This study will compare two different versions of an oral remdesivir drug in 48 healthy Chinese adults. Participants will receive both forms at different times to see how the body absorbs and processes each one. The goal is to understand if the new formulation works similarly to …

This study looks at how the brain uses feedback to control speech in 90 adults aged 18-50, including people who stutter, have dyslexia, and those with typical speech. Participants will do speech tasks, have MRI scans, and receive mild brain stimulation to understand differences i…

This study compares how people with migraine and healthy volunteers imagine movements, and looks at whether these mental abilities are linked to body awareness, balance, anxiety, and depression. About 136 adults aged 18-65 will take part, using questionnaires, mental tasks, and b…

This study looks at what makes it easier or harder for Turkish young people (ages 15-24) to be physically active. Researchers will survey 318 healthy volunteers about their activity levels, stress, and daytime sleepiness. The goal is to understand these factors so better programs…