HEALTHY PARTICIPANTS

This early-stage study tests a new vaccine called VXB-251 in 240 healthy adults aged 60-83. The vaccine targets three viruses (RSV, hMPV, and PIV3) that can cause serious lung infections. Researchers want to see if combining all three parts is safe and helps the immune system res…

This study looks at whether two herbal supplements, CL19183 and CL24212, can help overweight adults lose weight and improve their health. About 150 healthy but overweight people (BMI 25-30) aged 25-55 will take either the supplements or a placebo, while also following a diet and …

This early-stage study tests a new medicine called AZD0780 in 40 healthy adults who have high LDL ("bad") cholesterol. The main goal is to see if the drug safely lowers cholesterol levels compared to a placebo. Participants will take the drug or placebo by mouth and be monitored …

This study tests whether a virtual reality (VR) game can help primary schoolchildren aged 6-12 learn and practice better hygiene to prevent the spread of COVID-19 and other respiratory viruses. About 2,160 children will either play the VR game for two weeks or receive no extra tr…

This study tests whether giving repeated annual doses of an experimental drug called CD388 is safe for healthy adults. About 400 people who already tolerated one dose will receive two more doses over two years. Researchers will monitor for side effects and check if the body makes…

This study looks at whether giving a high-dose flu vaccine together with a new long-acting antiviral drug (CD388) is safe and still allows the body to build a strong defense against the flu. About 100 healthy adults aged 18 to 49 will get either the vaccine plus CD388 or the vacc…

This study tests a new surgical approach called Gingivalstat against the standard crown-lengthening surgery for people with a gummy smile (too much gum showing). The goal is to see which method keeps the gum line more stable and looks better over six months. Twenty-two healthy ad…

This study looked at whether taking magnesium citrate (400 mg daily for 90 days) could improve sleep quality and thinking skills in healthy Saudi adults who had poor sleep. Researchers compared 41 adults who took the supplement to a group that took nothing. The goal was to see if…

This study looks at whether doing very short, intense bike sprints (just 10–20 seconds each) twice a week can improve heart and lung fitness in inactive adults. Sixty healthy but inactive participants will do these sprints for 9 weeks, and their results will be compared to a grou…

This study tests whether focused ultrasound can alter the effects of propofol, a common anesthesia drug, in healthy adults. Ten participants will receive both real and fake ultrasound during sedation while researchers measure brain signals and responsiveness. The goal is to under…

This study looks at whether a special breathing warm-up can make athletes' breathing muscles stronger during exercise. About 28 trained athletes aged 14-30 will try three different warm-up routines: a breathing warm-up, a fake (placebo) breathing warm-up, and no warm-up at all. T…

This study checks if new combination tablets of nirmatrelvir and ritonavir are absorbed by the body just like the current Paxlovid tablets. About 28 healthy adults will take single doses of both tablet types under fasting conditions. The goal is to see if the new tablets are bioe…

This study looks at how a new drug called AZD5004 changes the way the body processes two diabetes medications, mitiglinide and pioglitazone. It involves 32 healthy volunteers and is not meant to treat any disease. The goal is to gather safety and drug-level information for future…

This study looks at how a single session of Swedish massage or light touch therapy changes brain activity, heart rate, blood pressure, and mood in healthy adults. Thirty participants will be randomly assigned to receive one type of touch therapy. Brain scans (MRI) are taken befor…

This study aims to develop better tools to measure thinking skills and everyday function in healthy older adults. Researchers will compare new computerized tests to standard ones over one year. The goal is to find measures that are more accurate and less affected by practice, whi…

This study looks at whether four one-hour coaching sessions with a psycho-oncologist can help doctors and nurses who treat cancer patients. The goal is to improve how they communicate with patients and handle difficult emotions. The study will involve 62 oncology and hematology c…

This study tests whether a single tablet containing two drugs (laroprovstat and rosuvastatin) works as well as taking each drug separately. It involves 44 healthy adults aged 18 to 55 who will receive both the combination and individual tablets at different times. The goal is to …

This study tests a new drug called QL2106 against an approved drug, Tremfye®, in 190 healthy adults aged 18-45. The goal is to compare how the body processes each drug, their safety, and whether the body makes antibodies against them. Participants receive a single dose and are mo…

This study looks at whether a special education program on patient safety can shift the way nursing leaders and educators in a Saudi medical city think about safety culture. About 102 head nurses, assistant head nurses, and educators will fill out a survey before the training, th…

This early-stage trial tests the safety of a new drug called STAR-0310 in 40 healthy adults. Participants receive a single dose of the drug or a placebo, and researchers monitor for side effects. The goal is to gather safety data, not to treat any disease.

This study tests whether a simple pillow can be as effective as a standard manikin for teaching CPR to non-healthcare professionals. Researchers will compare compression depth, number of compressions, and hand position in 128 healthy adults. The goal is to find a more affordable …

This early-stage study is testing a new drug, AZD0292, in 18 healthy Japanese adults to see if it is safe and how the body processes it. Participants receive a single dose of the drug or a placebo by IV. The main goal is to check for side effects and measure drug levels in the bl…

This early-stage study tests whether a new mRNA medicine called mRNA-0184 is safe in healthy people. About 52 volunteers will receive one or more doses under the skin. Researchers will monitor for side effects and measure how the drug moves through the body. This study does not a…

This study looks at brain activity and heart rhythms in 45 people — some who had a stroke and some who are healthy. Using special head sensors and a heart monitor, researchers want to see how stroke changes these signals. The goal is to better understand stroke's effects, not to …

This early-stage study tests a new drug called INCA033989 in 72 healthy adults aged 18 to 55. The goal is to see how the drug moves through the body and whether it is safe when given as a shot under the skin or through an IV. Participants will be monitored for side effects and dr…

This study compares two different devices for giving trastuzumab as a shot under the skin. It involves 312 healthy men to see if the drug levels in the body are similar between the devices. The goal is to check safety and how the body handles the drug, not to treat any disease.

This study tests whether a new biosimilar medicine (CT-P52) works like the approved drug Taltz in the body. About 218 healthy adults aged 19 to 55 will receive a single dose of either CT-P52 or Taltz. Researchers will measure how the drug levels and safety compare between the two…

This study aims to figure out the best schedule for follow-up visits for people who wear contact lenses. Researchers will track 300 healthy adults, both new and experienced lens wearers, to see how many visits are needed to keep eyes safe and healthy. The goal is to create clear …

This study in 8 healthy men aged 30-65 tracks how the investigational drug AZD4144 is absorbed, broken down, and eliminated from the body. Participants receive a single dose either by mouth or injection, with a tiny radioactive label to follow the drug. The goal is to understand …

This early-stage study is testing a single dose of a new drug called AG-236 in 24 healthy adults aged 18 to 55. The main goal is to see if it is safe and how the body processes it. No treatment for any disease is being tested here.

This study tests three different tablet versions of an experimental drug called LY4100511 in 48 healthy adults. Researchers want to see how well each version is absorbed by the body, and whether taking a common stomach acid medication changes that absorption. The goal is to pick …

This pilot study looked at whether listening to self-chosen Levantine music can change how healthy young adults feel pressure pain. 32 participants were tested in silence and while listening to their own music. The goal was to see if music can help reduce pain sensitivity and imp…