Morning vs. evening workouts: which blunts pain better?

NCT ID NCT07290465

Knowledge-focused Sponsor: Medipol University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether exercising at different times of day changes how we feel pain. Fifty-six healthy adults will do a 12-minute high-intensity workout in both the morning and evening. Researchers will measure pain thresholds before and after exercise to see if time of day, sleep type, or sex makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: High-Intensity Functional Training (HIFT) exercise session
What this could lead to: If successful, this study could help design better exercise-based pain management programs that consider the time of day.
What could go wrong: This is a small, early-stage study in healthy volunteers, not patients. Results may not apply to people with chronic pain or other conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 56 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy participants * age 18 to 40 years * good level of English that allow the enrolled participant to provide informed consent and complete the questionnaires provided * being categorized as "moderate" in the International Physical Activity Questionnaire (IPAQ) Exclusion Criteria: * inability to report pain intensity reliably * consumption of narcotics or tobacco products * regularly taking pain medications and analgesics * pregnant or planning to get pregnant * surgery within the last 12 months * acute or chronic pain conditions * uncontrolled hypertension * cardiovascular diseases, pulmonary diseases, neurological diseases with significant changes in somatosensory and pain perception, metabolic diseases, serious systemic diseases or conditions that restrict normal daily activities, inflammatory conditions (e.g. rheumatoid arthritis), or orthopedic injuries * intolerable pain during the pain perception test * serious psychiatric conditions (e.g., schizophrenia and bipolar disorder) or psychological disorders (e.g., depression) that may affect pain thresholds (16). * Severe sleep disorders and circadian rhythm disturbances * BMI \> 30 * serious fatigue or delayed-onset muscle soreness (9) at least 24 h after exercise sessions or a sudden change in activity for more than one week

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Conditions

The condition(s) this trial relates to.

agnosia circadian rhythm sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronotype Circadian rhythm Exercise induced hypoalgesia Healthy participants Pain perception Physical therapy

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

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Morning vs. evening workouts: which blunts pain better?

What the study statuses mean